Respiratory Flashcards
What is Croup?
Viral laryngotracheobronchitis.
What are the risk factors for croup?
- FHx
- LBW / Prematurity
- Autumn / Winter
- M > F
What are the causes of croup?
- Main cause = Parainfluenza
- Other causes
- RSV
- Rhinovirus
- Influenza
What are the signs and symptoms of croup?
- Affects 6 months to 6 years → 2 years = peak
- Acute onset of - over days
- Coryzal symptoms
- “Barking cough” - from vocal cord impairment
- Stridor - from inflamed/oedematous airways
- Hoarse voice
What are the appropriate investigations for suspected croup?
- Clinical
- Obs
- Do NOT examine throat
How is croup classified?
Westley score
- Mild = 0-2
- Moderate = 3-7
- Severe = 8-11
- Impending respiratory failure = 12-17
What is the management of croup?
- Mild (Westley 0-2) = Oral Dexamethasone + Discharge
- Moderate (Westley 3-7) = Nebulised Dexamethasone + Admission
- Severe (Westley 8-11) = Nebulised Dexamethasone ± Adrenaline + Admission
- Impending respiratory failure (RR >70 and/or Westley 12-17) = Nebulised Dexamethasone ± Nebulised Adrenaline + O2 Admission ± ITU
What are the complications of croup?
- Secondary bacterial superinfection
- Pulmonary oedema
- Pneumothorax
What counselling should be given to child/parents with a child with croup?
- Explain diagnosis -common viral infection of the airways
-
Explain that it gets better over 48 hours and steroids help
- Paracetamol or ibuprofen if distressed
- Advise good fluid intake
- Safety net:
- Advise regularly checking on the child at night - cough is worse
- If it gets worse = come back
- If the child becomes blue or very pale for more than a few seconds, unusually sleepy or unresponsive or serious breathing difficulties call an ambulance
What are the causes of bronchiolitis?
- RSV (80%)
- Parainfluenza
- Rhinovirus
- Adenovirus
- Influenza
- Human metapneumovirus (rare → PICU care)
- Co-infection = more severe illness
- RSV highly infectious so infection control measures
What is the progression of bronchiolitis?
Bronchiolitis (0-1yo) → Viral-induced/episodic Wheeze (1-5yo) → Asthma (>5yo)
What are the risk factors for bronchiolitis?
- Pre-term/BPD
- Passive smoking
- LBW
- Chronic heart disease
- Hypotonia
- Winter
- Protective = BREASTFEEDING
What are the complications of bronciolitis?
Can cause permanent airway damage - bronchiolitis obliterans
- Rare
What are the signs and symptoms of bronchiolitis?
- <1 year old → 2-3% of infants are admitted with it
- Coryzal symptoms → progressive to below
- Dry wheezy cough
- SoB
- Grunting
- High RR/HR
- Subcostal/intercostal recessions
- Hyperinflation
- Auscultate – how to differentiate from croup/other ‘-itits’
- Fine, bi-basal, end-inspiratory crackles
- High-pitch expiratory wheeze
- Feeding difficulty → admission
What are the appropriate investigations for?
- Clinical diagnosis with SpO2 → can do NPA to confirm
- If there is significant respiratory distress + fever = CXR to rule out pneumonia
What is the management of bronchiolitis?
-
Supportive
- Nasal O2 + NG fluids/feeds ± Nebulised 3% saline → CPAP (if respiratory failure)
- <6m old = no beta receptors in lungs so salbutamol won’t work – would give it if over 1yo
- If high-risk preterm infant (BPD, congenital HD, immunodeficiency) = Palivizumab (monoclonal Ab vs RSV)
- Hospital admission
- <2m = lower threshold as deteriorate quick
- Apnoea / Central cyanosis / Grunting
- SpO2 <92% on room air
- Poor oral fluid intake (≤50% normal in <24hrs)
- Severe respiratory distress (i.e. RR>70)
Define Rhinitis.
Common cold causing acute and self-limiting inflammation of URT mucosa, involving nose, throat, sinuses or larynx.
What is the most common infection in childhood?
Rhinitis
What are the causes of rhinitis?
- Rhinovirus (50%)
- Coronavirus (10%)
- Influenza (5%)
- Parainfluenza (5%)
- Human respiratory syncytial virus (5%)
What are the signs and symptoms of rhinitis?
- Clear/mucopurulent discharge
- Nasal block
What are the appropriate investigations for suspected rhinitis?
Clinical diagnosis
What is the management of rhinitis?
-
Health education
- Self-limiting
- No Abx - virus
- May reduce anxiety and unnecessary visits to doctor
- Cough may last 4 weeks after cold → generally recover after 2 weeks
- Pain = Paracetamol or Ibuprofen
- Potentially Decongestants or Antihistamines
What are the complications of rhinitis?
- Otitis media
- Acute sinusitis
Define Sinusitis.
Infection of the maxillary sinuses from viral URTIs which can get a secondary bacterial infection.
- Unlikely to be frontal sinus → don’t develop until after 10 years old
What are the signs and symptoms of sinusitis?
- Pain, swelling and tenderness on front of face
- Influenza-like illness
What are the appropriate investigations for suspected sinusitits?
Clinical diagnosis
What is the management of sinusitis?
- Symptoms lasting <10 days
- No antibiotic
- Advice → virus, takes 2-3 weeks to resolve, only 2% get bacterial complication, simple analgesia, nasal saline or nasal decongestants
- Symptoms lasting >10 days
-
High-dose nasal corticosteroid for 14 days (if >12yo; e.g. mometasone)
- May improve symptoms but unlikely to affect duration of illness
- Abx not indicated → can give back up prescription if symptoms don’t get better in 7 days or if symptoms get rapidly worse
- 1st line = phenoxymethylpenicillin (clarithromycin if penicillin-allergic)
- 2nd line: co-amoxiclav
-
High-dose nasal corticosteroid for 14 days (if >12yo; e.g. mometasone)
- Refer to hospital if there are symptoms and signs of
- Severe systemic infection
- Intraorbital or periorbital problems
- Intracranial complications / Features of meningitis
What are the risk factors for viral-induced wheeze?
- Maternal smoking (ante-/post-natal)
- Prematurity
- FHx of viral-induced wheeze
What are the signs and symptoms of asthma?
- Wheeze - end-expiratory polyphonic
- Cough
- SoB
-
Chest tightness
- Symptoms worst at night / early morning
- Symptoms with non-viral triggers
- Personal or FHx of atopy
- Positive response to asthma bronchodilator therapy
- Examination
- Hyperinflated chest ± accessory muscle use
- Harrison’s sulci - depressions at base of thorax where diaphragm has grown in muscular size
What are the appropriate investigations in to suspected asthma in a child under the age of 5?
Clinical diagnosis
What are the appropriate investigations in to suspected asthma in a child over the age of 5?
-
Clinical + Picture
- Spirometry - FEV1/FVC <70%
- Bronchodilator - 12% pre/post difference
What are the signs of a moderate asthma attack in a child?
- PEFR = 50-75%
- Normal speech
What are the signs of a severe asthma attack in a child?
- PEFR = 33-50%
- RR
- 2-5 years = >40
- 5-12 years = >30
- >12 years = >25
- HR
- 2-5 years = >140
- 5-12 years = >125
- >12 years = >110
- SpO2 = >92%
- Inability to complete sentences in one breath
- Accessory muscle use
- Inability to feed
What are the signs of a life-threatening asthma attack in a child?
- PEFR = <33%
- SpO2 = <92%
- PaCO2 = >4.8kPa
- Altered consciousness
- Exhaustion
- Cardiac arrhythmia
- Hypotension
- Cyanosis
- Poor respiratory effort
- Silent chest
What is the management of a moderate asthma attack?
- No admission needed
- Salbutamol - 4-hourly up to max 4/day
- Oral prednisolone - for 3d
- Follow-up in 48hrs
What is the management of a severe to life-threatening asthma attack?
- Admit to hospital/A&E
- Burst step
* O2 therapy (maintain SpO2 >92%)
* 3x Salbutamol nebs / 10 inhales on a pump
* 2x Ipratropium bromide nebulisers
* 1x oral Prednisolone (benefit after 4-6h)
- Burst step
- IV bolus step
* IV bolus MgSO4 + one of the below
* IV bolus Salbutamol
* IV bolus Aminophylline- Monitor ECG → both can cause arrhythmias
- IV bolus step
- IV infusion step – one of the below
* IV Salbutamol
* IV Aminophylline
- IV infusion step – one of the below
- Panic step
* Intubate and ventilate + Transfer to ICU
- Panic step
- Once stabilised = Salbutamol 1-hourly → 2-hourly → 3-hourly → 4-hourly → Home when:
- Stable on 4-hourly treatment - further wean at home
- Peak flow at 75% of best predicted
- SpO2>94%
- Follow-up within 2 days of discharge
- Patient Education
What are the contraindications for beta-agonists (salbutamol)?
- Beta blockers
- NSAIDs
- Adenosine
- ACEi
What is the outpatient management of asthma in a child?
-
SABA - Salbutamol PRN → Step up when using inhaler ≥3x a week
- Can use a spacer if young or difficulty using
- Do not exceed 4-hourly puffs (i.e. 4 puffs a day)
- Low dose ICS - Becotide (Beclomatsone dipropionate)
-
Leukotriene Receptor Antagonist - Oral Montelukast
- Review after 4-8w
- 5-16yo = if fail on review, switch LTRA to LABA
- <5yo = if fail on review, stop LTRA and refer to specialist
- Review after 4-8w
-
Increased ICS dose - Flixotide (Fluticasone propionate)
- Consider reducing dose once asthma controlled
-
Oral steroid - Prednisolone
- Lowest dose to maintain control
- Managed by specialist
How common is acute otitis media?
- Very common - Most children have 1 episode
- Young eustachian tubes are short, horizontal and function poorly → middle ear infection