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Leeds MBCHB Year 4 CCC > Respiratory > Flashcards

Respiratory Flashcards

1
Q

Common tiggers for asthma

A 
Infection
Night time or early morning
Exercise
Animals
Cold/ damp
Dust
Strong emotions
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2
Q

When in the day is asthma worse

A

Early morning and late at night (worst)

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3
Q

What is heard when listening to an asthmatics chest

A

Bilateral widespread polyphonic wheeze

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4
Q

NICE first line investigations for asthma

A

Fractional exhaled nitric oxide

Spirometry with bronchodilator reversibility

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5
Q

What investigations to do if diagnostics uncertainty in asthma

A

Peak flow variability by keeping a diary of readings several times a day for two weeks
Direction bronchial challenge with histamine

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6
Q

What type of drug is tiotropium

A

LAMA

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7
Q

How do LAMAs work

A

Block ach receptors from parasynthetic nervous system

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8
Q

Why is theophylline rarely used in community

A

Narrow therapeutic window (blood test 5 days after starting and then every 3 days)

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9
Q

NICE guidelines for asthma

A

SABA
ICS
LRA
LABA

MART regime
Theophylline

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10
Q

Does COPD cause clubbing

A

NO

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11
Q

How to make a dx for COPD

A

Clinical picture and spirometry

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12
Q

COPD FEV1/FEV ratio

A

Less than 0.7 (obstructive)

Will show no change with salbutamol

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13
Q

What is the severity of airway obstruction in COPD based upon

A

FEV1

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14
Q

FBC changes in COPD

A

Polycythaemia (chronic hypoxia)

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15
Q

Serum alpha-1 antitrypsin deficiency would cause

A

COPD

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16
Q

What two vaccines should COPD patients receive

A

Pneumococcal and annual flu

17
Q

Test for diagnostic certainty in COPD

A

TLCO

Decreased (may be increased in other conditions such as asthma)

18
Q

Acute asthma management

A

O SHIT ME

O2 
Salbutamol
Hydrocortisone/ pred (5 days)
Ipratropium bromide
Theophylline/ aminiphylline
Magnesium sulfate
Intubation
19
Q

Sacale for dyspnoae

A

MRC

Medical research council

Leeds MBCHB Year 4 CCC (7 decks)

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