respiratory

Question 1

Bronchodilator, beta adrenergic agonist and their receptors

Answer 1

epinephrine: alpha, beta 1, beta 2
isoproterenol: beta 1, beta 2
metaproterenol: beta 1, beta 2

Question 2

Short acting bronchodilators, how long do they last?

Answer 2

Albuterol

Levalbuterol

turbutaline

Salbutamol

4-6 hrs

Question 3

Long acting bronchodilator, how long?

Answer 3

salmeterol, 12 hrs

Question 4

how does beta adrenergics work?

Answer 4

activates adenlyl cyclase, increase cAMP, decrease IC Ca, bronchodilation

Question 5

Primary effect of bronchodilators

Answer 5

bronchodilation

inhibit mediator release

increase mucus clearance

Question 6

beta bronchodilator side effects

Answer 6

minimized by inhalation delivery

tremor

increased HR

vasodilatoins

metabolic changes: hyperglycemia, hypokalemia, hypomagnesemia

Question 7

albuterol doses and DOA

Answer 7

90-100mcg/puff

2 puffs q4-6 hrs

Nebulizer 2.5-5mg in 5ml of saline

4 hrs with some relief up to 8 hrs

Question 8

terbutaline SC dosage

Answer 8

child: 0.01mg/kg

Adult: 0.25mg q15min, you can give twice, and that’s all you can give q4h

16-20 puffs/day

each puff is 200mcg