antimicrobial Flashcards

1
Q

Surgical risk for SSI

A
  • Surgical type
  • Surgeon skill
  • Use of foreign material or implantable device
  • degree of tissue trauma
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2
Q

SSI patient risk

A
  • DM
  • Smoking
  • Obesity
  • Malnutrition
  • hypothermia
  • Steroid use
  • immunosuppressive therapy
  • Trauma
  • Prosthetic heart valve
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3
Q

Vancomycin timing

A

IV over an hour, ideally should be over 2hrs ahead of time.

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4
Q

SBE prophyalxis drug and dosage

A

Amoxicillin 2gms, P.O.

Ampicillin, 2gms, IV

If Penicillin allergic:

Ceftriaxone 1gm IV

Cefazolin 1 gm IV (not in pt hypersensitive to PCN)

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5
Q

Bacteriostatic medications

A
  • Chloramphenicol
  • Clindamycin
  • Macrolides
  • Sulfonamides
  • Tetracyclines
  • Trimethroprim
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6
Q

Bactericidals

A
  • Penicillin’s & Cephalosporin’s
  • Isoniazid
  • Metronidazole
  • Polymyxins
  • Rifampin
  • Vancomycin
  • Aminoglycosides
  • Bacitracin
  • Quinolones
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7
Q

Vancmycin dose

A

10-15 mg/kg over 60 min

1g mixed in 250ml saline

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8
Q

Side effect of antiviral

A
  • Flu like syndromes
  • hematologic toxicity
  • Depression, irritability
  • decreased mental concentration
  • development of autoimmune diseases
  • rashes, alopecia
  • changes in CV, thyroid, hepatic function
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