respi - buzzwords for asthma and copd drugs Flashcards
asthma attack w severe symptoms
epinephrine
short-acting bronchodilator, causes tremors and tachycardia
salbutamol
long-acting bronchodilator, twice daily, for maintenance and relief, cause tremors and palpitations
formoterol
controller, slow-acting bronchodilator, causes tremors and palpitations
salmeterol
severe COPD, LAMA does not work, once-daily long-acting bronchodilator, causes tremors and palpitations
indacaterol
short-acting adjunct bronchodilator, causes dry mouth and unpleasant taste
ipratropium bromide
1st line for copd, causes dry mouth, unpleasant taste, urinary retention
tiotropium
adjunct bronchodilator, causes nervousness, anxiety, insomnia, arrhythmias, narrow therapeutic window
theophylline
anti-inflam adjunct, anti-fibrotic, causes diarrhoea, weight loss, insomnia, depression, suicide ideation
roflumilast
anti-inflam adjunct, hepatotoxicity, mood changes, insomnia, suicidal ideation
zileuton
anti-inflam adjunct, causes mood disturbances, vivid dreams, suicidal thinking, eosinophilia, small-veseel vasculitis, churg-strauss syndrome
montelukast
adjunct inhaler, throat irritation, dry mouth, cough, unpleasant bitter taste
cromoglicic acid
controller, to reduce reliance on SABA, causes oral thrush, hoarseness, adrenal suppression
ICS
targets IgE, causes heart attack
omalizumab
target IL-5
reslizumab (resli - 5 letters)
targets IL-4/IL-13
dupilumab (dupi - 4 letters)
anti-fibrotic, risk of QT prolongation, contraindicated in hepatic dysfunc
azithromycin
persistent thick sputum, reduce sputum viscosity
erdosteine
