Resp Flashcards
What are the main pathological features in childhood asthma?
Inflamed airways
Hypersensitivity
Airway remodelling
Which cells mediate the inflammation in asthma?
Eosinophils and CD4+
What is the classic presentation of asthma?
Wheeze, cough, chest tightness, dyspnoea
What are common asthma triggers?
Cold
Exercise
Allergens
Stress
What will PEFR investigation show for asthma?
Low for age/height
Better at rest and with a bronchodilator
What will spirometry show for asthma?
15% improvement in FEV1 following inhalation of bronchodilator
How is asthma managed chronically?
Stepwise ladder
SABA»_space; +ICS»_space; + LABA»_space; + LTR antagonist»_space; + oral steroids
Which inhaler devices should be used in asthma 0-2 years?
Spacer + mask
Which inhaler devices should be used in asthma 2-7 years?
MDI + spacer
Outline acute management of asthma:
Oxygen Salbutamol nebulised Ipratropium nebulised IV hydrocortisone MgSO4
What is the most common cause of bronchiolitis?
RSV
Give risk factors for bronchiolitis:
Prem; chronic resp conditions; CHD
Which age group get brnociolitis?
Under 18m
How does bronchiolitis present?
Wheeze, dry cough, fever, nasal flaring, increased WOB, difficulty feeding
What is found on examination of bronchiolitis?
Fine insp crackles
Exp wheeze
How is bronchiolitis invesigated?
Tends to not be unless severe
If severe: nasopharyngea laspirate, blood gas, CXR