resp

Question 1

COPD exacerbation at home

Answer 1

prednisolone 30mg and inhalers

Question 2

COPD exacerbation at hospital

Answer 2

salbutamol 5mg/4hr and iptratropium 500mg/6h

hydrocortisone 200mg OR prednisolone 30-40mg

Question 3

severe COPD exacerbation

Answer 3

IV aminophylline

doxapram

Question 4

COPD long term management

Answer 4

1. SABA (Salbutamol or terbutaline) or SAMA (ipratropium bromide)
   2a. no response: add LABA and LAMA
   2b. response: add LABA and ICS
2. no response to 2b = add LAMA

Question 5

acute asthma attack: moderate

Answer 5

nebuliser salbutamol and ipratropium bromide
+
oral prednisolone OR IV hydrocortisone

Question 6

acute asthma: severe

Answer 6

IV aminophylline

IV salbutamol

Question 7

acute asthma: life threatening

Answer 7

magnesium sulfave IV

intubation, ICU

Question 8

asthma management. stepwise

Answer 8

1. SABA
2. • low dose ICS
3. • LABA (salmeterol)
     4a: no benefit: stop LABA, increase ICS dose
     4b: benefit: continue LABA, increase ICS dose
4. trial oral leukotriene receptor antagonist

Question 9

asthma bronchodilators: SABA

Answer 9

salbutamol

Question 10

asthma bronchodilators: LABA

Answer 10

salmererol
formoterol
vilanterol (72hrs)

Question 11

asthma bronchodilators: SAMA

Answer 11

ipratropium

Question 12

asthma bronchodilators: LAMA

Answer 12

tiotropium

umeclidinium

Question 13

long acting ICS

Answer 13

fluticasone furoate

Question 14

new asthma drugs: targets inflammatory response

Answer 14

benralizumab
mepolizumab and reslizumab

IL-5

Question 15

new asthma drugs: targets allergic response

Answer 15

omalizumab

lower IgE

Question 16

what is recommended for patients with AERD

Answer 16

LTRA - leukotriene receptor antagonist

e.g. montelukast