Resp Flashcards
Causes of chronic interstitial lung disease?
idiopathic
rheumatological (RA,SLE, Sjogrens, dermatomyositis, Ank Spond, psoriasis, systemic sclerosis)
drugs (methotrexate, trimethoprim, amiodarone, bleomycin)
inhaled (extrinsic allergic alveolitis, asbestosis, silicosis, beryliosis)
vasculitis (Wegner’s, polyarteritis nodosa, Churg-Strauss, Goodpasture’s)
TB, sarcoid
Respiratory causes of clubbing
bronchiectasis lung cancer interstitial lung disease CF lung abscess TB mesothelioma
Which conditions cause predominantly Apical fibrosis?
BREASTS CLAP
Berylliosis, radiation, extrinsic allergic alveolitis, aspergillosis, silicosis, TB, sarcoidosis, coal miner’s pneumoconiosis, langerhans cell histiocytisis, ank spond, psoriasis
Causes of COPD
smoking
alpha 1 antitripsin deficiency
coal dust
common pathogens of IECOPD
strep pneumonae
Haemophilus influenzae
moraxella catarrhalis
indications for long term oxygen
stopped smoking
pO2
What is Light’s criteria for an exudate?
pleural fluid protein:serum protein >0.5
pleural LDH:serum LDH >0.6
pleural LDH >2/3rds upper limit of normal serum value
DDx for dullness and dull percussion at a lung base?
pleural effusion consolidation collapse tumour pleural thickening raised hemidiaphragm lobectomy (+scar)
causes of a chylothorax (pleural fluid cholesterol >4g/l)
lymphatic obstruction (lymphoma or solid tumour)
lymphatic damage (post surgery)
nephrotic syn
cirrhosis
causes of low pleural fluid glucose/pH
malignancy TB empyema inflammation - RA, SLE oesophageal rupture
Organisms involved in an empyema
anaerobes
staph
gram neg organisms (legionella, moraxella, Haemophilus)
Ddx of clubbing and crackles
bronchiectasis
fibrosing alveolitis
chronic lung abscess
bronchial carcinoma
causes of bronchiectasis
congenital - Kartageners and CF
mechanical obstruction - bronchial carcinoma
childhood illness - TB and measles
immune OVER activity - allergic bronchopulmonary aspergillosis, IBD associated
immune UNDER activity - hypogammaglobulinaemia
aspiration - chronic alcoholics and GORD