Resp Flashcards
Mitochondria structure to function
- Small size
- Outer membrane
- Outer and inner membrane
- Inner membrane
- Matrix
Mitochondria size to function
Small size
↑ SA:V = efficient diffusion of respiratory intermediates and ATP between cytoplasm and mitochondria + easier movement in cell to areas where ↑ energy demand
Mitochondria outer membrane.
Outer membrane
Compartmentalisation → separate contents of mitochondria from cytoplasm
- ✓ specialised metabolic pathways occur inside mitochondria in optimal conditions
- ✓ regulate passage of substances in and out of mitochondria
○ Entry of pyruvate and O2, exit of ATP
Contains membrane proteins that function to shuttle H from NADH in cytoplasm to NAD in mitochondrial matrix (NAD ✕ pass through membrane)
Mitochondria outer and inner
Outer and inner membranes
Enclose inter membrane space + impermeable to H+ = ✓ accumulate H+ in inter membrane space = generate proton gradient and PMF
Mitochondria inner
Inner membranes
Attachment of e- carriers onto membrane → arrangement in specific order of progressively ↓ energy level to form ETC
✓ attachment of ATP synthase that catalyses ATP synthesis
Infolding into Cristae = ↑ SA of inner membrane
- ↑ e- carriers attached = ↑ ETC + ↑ ATP synthase attached
- ↑ accessibility of NADH and FADH2 to ETC
Contains specific protein channels (pyruvate translocase) for movement of specific materials → selectively permeable
Permeable to O2 and ATP
Mitochondria matrix
Matrix
Contains enzymes that catalyse reactions in link rxn and Krebs cycle + fatty acid β-oxidation
Contains mitochondrial DNA, RNA and ribosomes involved in synthesis of certain mitochondrial proteins