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1
Q

Mitochondria structure to function

A
  1. Small size
  2. Outer membrane
  3. Outer and inner membrane
  4. Inner membrane
  5. Matrix
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2
Q

Mitochondria size to function

A

Small size

↑ SA:V = efficient diffusion of respiratory intermediates and ATP between cytoplasm and mitochondria + easier movement in cell to areas where ↑ energy demand

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3
Q

Mitochondria outer membrane.

A

Outer membrane

Compartmentalisation → separate contents of mitochondria from cytoplasm
- ✓ specialised metabolic pathways occur inside mitochondria in optimal conditions
- ✓ regulate passage of substances in and out of mitochondria
○ Entry of pyruvate and O2, exit of ATP

Contains membrane proteins that function to shuttle H from NADH in cytoplasm to NAD in mitochondrial matrix (NAD ✕ pass through membrane)

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4
Q

Mitochondria outer and inner

A

Outer and inner membranes

Enclose inter membrane space + impermeable to H+ = ✓ accumulate H+ in inter membrane space = generate proton gradient and PMF

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5
Q

Mitochondria inner

A

Inner membranes

Attachment of e- carriers onto membrane → arrangement in specific order of progressively ↓ energy level to form ETC

✓ attachment of ATP synthase that catalyses ATP synthesis

Infolding into Cristae = ↑ SA of inner membrane
- ↑ e- carriers attached = ↑ ETC + ↑ ATP synthase attached
- ↑ accessibility of NADH and FADH2 to ETC

Contains specific protein channels (pyruvate translocase) for movement of specific materials → selectively permeable
Permeable to O2 and ATP

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6
Q

Mitochondria matrix

A

Matrix

Contains enzymes that catalyse reactions in link rxn and Krebs cycle + fatty acid β-oxidation

Contains mitochondrial DNA, RNA and ribosomes involved in synthesis of certain mitochondrial proteins

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