Dna Structure To Function

Question 1

Acronym (functions)

Answer 1

Bs GASM

Base sequence
Genetic variation
Accurate replication
Stability
Mutations (prevent)

Question 2

Sequence of bases

Answer 2

Long polymer → large amount of genetic info → coded info

Question 3

Genetic variation

Answer 3

Mutations in DNA → new stable forms

Question 4

Accurate replication

Answer 4

DNA Rep via CBP between nitrogenous bases
Double helical structure → ✓ semi conservative rep
Each strand acts as template → 2 daughter DNA molecules with identical structure and sequence

Question 5

Stability

Answer 5

H bonds between N bases
Strong covalent phosphodiester bonds between nucleotides
Hydrophobic interactions in nitrogenous bases stacking
No -OH on 2C on deoxyribose = ↓ reactivity
Wrapping of DNA around histone proteins = ↓ negative charge, acidity

Question 6

Mutations (prevent)

Answer 6

DNA repair using intact complementary template stand

Question 7

DNA replication rough outline

Answer 7

1. Helicase
2. Single stranded dna binding protein
3. Primase
4. DNA pol III
5. DNA pol I
6. Ligase