resp Flashcards
The following is a good choice for relieving headache in an asthmatic patient with aspirin hypersensitivity:
Aspirin Diclofenac Paracetamol ibuprofen prednisolone
Paracetamol
the following is useful for prevention of exacerbations in a patient with severe chronic bronchitis: • Methylprednisolone • Prednisolone • Cromolyn • salbutamol • roflumilast
• roflumilast
. Which medication is best to recommended for a 10-year-old patient with asthma, in addition to salbutamol MDI 1 or 2puffs every 4-6 hours as needed?
• Oral
• No additional therapy needed.
• Budesonide/formoterol MDI 80/4.5 mcg per puff 2 puffs
twice daily.
• Mometasone DPI
• Mometasone DPI
A 52-year-old 172 cm tall Asian man, has: FEV1 of 1.53L and FVC of 2.72L. This patient is expected to have:
• Mild airflow obstruction as evidenced by the low FEV1 and normal EFV1 /FVC%
• Moderately severe airflow obstruction as evidenced by the low FEV1 and low EFV1 /FVC%
• Severe airflow obstruction as evidenced by the low FEV1 and low EFV 1 /FVC%
• Moderate airflow restriction as evidenced by the low FEV1 and high EFV 1 /FVC%
• Moderate airflow restriction as evidenced by the low FEV1 and normal EFV 1 /FVC%
• Moderately severe airflow obstruction as evidenced by the low FEV1 and low EFV1 /FVC%
How many seconds is optimal for breath holding after inhaling fromanMDI? 12 10 20 30
10
The underlying pathophysiology of asthma is best described by which of the following statements?
• Asthma is a psychosomatic disorder.
• Asthma is a disorder of the lung parenchyma.
• Asthma is caused by an aberrant response to
vaccinations.
asthma is a disease of airway inflammation
asthma is a disease of airway inflammation
Which objective measure for routine monitoring of asthma is available at home?
• PACO2 • FVC
• FEV1
• PEFR
• PD20
• Asthma is a disease of airway inflammation.
• PEFR
- Oral medication are popular for the treatment of asthma in children because young children may have difficulty with the proper use of aerosol inhalers. Which of the following is an orally active drug used for asthma?
Ipratropium Cromolyn Salmeterol Montelukast
Montelukast
Which side effect of inhaled corticosteroids is reduced by spacer devices?
Cataracts Oropharyngeal candidiasis Thinning of skin Decreased bone density
Oropharyngeal candidiasis
The following class of drugs is indicated in severe COPD With frequent exacerbations is:
O Long-acting inhaled beta-2 agonists O Anticholinergics
O Inhaled corticosteroids
O Methylxanthines
O Short-acting inhaled beta-2 agonists
Inhaled corticosteroids
Which of the following drugs combinations is preferred for long-term management of moderate persistent asthma?: • Zafiukast + Ipratropium • Budesonide + Ipratropium • Budesonide + salmeterol • Aminophylline + formoterol
Budesonide + salmeterol
A patient with COPD is expected to have:
O Increased TLC, decreased VC, increased FEVI /FVC ratio
O Increased TLC, decreased VC, decreased FEVI/FVC ratio
O Increased TLC, decreased VC, normal FEVI/FVC ratio
O Decreased TLC, increased VC, increased FEVI /FVC ratio
Increased TLC, decreased VC, decreased FEVI/FVC ratio
Which objective measure for routine monitoring of asthma is available at home? • PACO2 • FVC • FEV1 • PEFR • PD20
• PEFR
. For patients with asthma or COPD exacerbations who are not responding adequately to inhaled medications. what is the agent of choice to add to manage the acute exacerbations?
• Budesonide Cromolyn Theophylline Prednisolone
Theophylline
Which of the following drugs does not have a direct bronchodilators effect?
Ipratropium Epinephrine Theophylline Prednisolone
Prednisolone
Which medications is best to recommended for 9-year-old girl with asthma, in addition to salbutamol MDI ? • Oral theophylline • No additional therapy is needed • Mometasone DPI • Budesonide/formoterol MDI
• Mometasone DPI
A 16-year-old male treated for bronchial asthma develops skeletal muscle tremors. Which of the following agents may be responsible for this finding?
Ipratropium zileuton salmeterol cromolyn Beclomethasone
salmeterol
19.Which is the best asthma maintenance therapy for a 20-year- old patient using salbutamol inhaler throughout the day on a daily basis and sometimes at night?
• Zileuton.
• Fluticasone low dose.
• Fluticasone high dose.
Fluticasone low dose.
A 20-year-old asthmatic patient needs salbutamol inhaler throughout the day on a daily basis and sometimes at night. Which of the following is the best maintenance therapy in this patient?
Beclomethasone low dose Beclomethasone high dose
eclomethasone low dose
A 22-year-old man come back home from abroad, He has a history of asthma, and best the summarizes the efficacy or current status of this drug in such patients?
• IS, at best, a second or third-line agent for long term asthma control
• Dosing is Simple and convenient. rarely needs be adjusted
• Excellent alternative to an inhaled steroid for “rescue” therapy
• Possesses strong and clinically useful anti-inflammatory activity
• IS, at best, a second or third-line agent for long term asthma control
A 23-year-old women is using salbutamol inhaler for frequent acute episodes of asthma and complains od symptoms that she ascribed to the salbutamol. Which of the following is not a recognized action of salbutamol?
Tachycardia Positive inotropic effect Diuretic effect Skeletal muscle tremor Smooth muscle relaxation
Diuretic effect
A 25-year-old woman is seen for follow-up of persistent asthma symptoms despite treatment with inhaled fluticasone 88microg twice daily for the past 3months, According to the Asthma treatment guidelines, which of the following changes in therapy can be considered?
• Addition of a leukotriene antagonist Addition of a low-dose theophylline Addition of a long-acting beta-agonist
• Increase the dose of ICS or add leukotriene antagonist or a LABA or low-dose theophylline.
• Increase the dose of ICS or add leukotriene antagonist or a LABA or low-dose theophylline.
A 40-year-old women with moderate persistent asthma has been under good control for 3 months (currently using salbutamol MDI once weekly). She awakens at night twice monthly with asthma symptoms but continues to exercise regularly without difficulties. Her other medications include fluticasone inhaled 88microg/puff twice daily and salmeterol 50 microg twice daily. Her FEV1 is currently at 83% of her personal best. Which action is most appropriate at the present time?
• Decrease the fluticasone to 44microg/puff twice daily
• Discontinue the fluticasone
• Do nothing, as the current salbutamol usage suggests poor
asthma control
• Discontinue the salmeterol
• Add Montelukast 10mg once daily, as the current
salbutamol usage suggests poor asthma control
Discontinue the salmetero
A 43-year-old women with moderate persistent asthma has been under good control for 4 months (currently needing salbutamol MDI once weekly or less). He awakenes at night twice monthly with asthma continues to exercise regularly without difficulties. His medications are low dose fluticasone inhaler and salmeterol inhaler. His FEV1 83% of her personal best. Which action is most appropriate at the present time?
• Decrease the fluticasone dose
• Discontinue the fluticasone
Do nothing, as the current salbutamol usage suggests poor asthma control
Discontinue the salmeterol
• Add Montelukast as a replacement for salbutamol
Discontinue the salmeterol