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PHRM 825 > Rescue Asthma Drugs in Asthma and COPD > Flashcards

Rescue Asthma Drugs in Asthma and COPD Flashcards

1
Q

Drug Class: Albuterol HFA

A

Inhaled SABA

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2
Q

Brand Name: Albuterol HFA

A

ProAir
Ventolin
Proventil
ProAir-Respiclick
ProAir Digihaler

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3
Q

Dosage Form: Albuterol HFA

A

Metered Dose Inhaler (MDI)
Aerosol Powser Inhaler (Respiclick and Digihaler)

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4
Q

Age Group Dosing: Albuterol HFA

A

all ages

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5
Q

Drug Class: Albuterol

A

Inhaled SABA

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6
Q

Brand Name: Albuterol

A

there isn’t one :(

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7
Q

Dosage Form: Albuterol

A

Nebulizer Solution

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8
Q

Age Group Dosing: Albuterol

A

all ages

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9
Q

Adverse Effects: Albuterol

A

tachycardia
tremor
hypokalemia
irritability

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10
Q

Clinical Pears: Albuterol

A

chronic use (>2x/day) indicates poor asthma control

may mix nebulizer solution with cromolyn solution, busesonide inhalent suspension, or ipratropium solution

in mild to moderate exacerbations, MDI plus valved holding chamber is as effective as nebulized therapy with appropriate administration technique and coaching by trained personally

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11
Q

Drug Class: Levalbuterol HFA

A

Inhaled SABA

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12
Q

Brand Name: Levalbuterol HFA

A

Xopenex

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13
Q

Dosage Form: Levalbuterol HFA

A

MDI

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14
Q

Age Group Dosing: Levalbuterol HFA

A

All Ages

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15
Q

Drug Class: Levalbuterol

A

Inhaled SABA

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16
Q

Brand Name: Levalbuterol

A

Xopenex

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17
Q

Dosage Form: Levalbuterol

A

Nebulizer Solution

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18
Q

Age Group Dosing: Levalbuterol

A

All Ages

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19
Q

Adverse Effects: Levalbuterol

A

tachycardia
tremor
hypokalemia
irritability

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20
Q

Clinical Pearls: Levalbuterol

A

reserved for patients who do not respond to albuterol for quick relief

nebulizer solution compatible with budesonide inhalent suspension

levalbuterol administration in 1/2 the mg dose of albuterol provides comparable efficacy and safety

has not been evaluated by continuous nebulization

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21
Q

Drug Class: Ipratropium HFA

A

SAMA

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22
Q

Brand Name: Ipratropium HFA

23
Q

Dosage Form: Ipratropium HFA

24
Q

Age Group Dosing: Ipratropium

25
Q

Dosage Form: Ipratropium

A

Nebulizer solution

26
Q

Age Group Dosing: Ipratropium

27
Q

Adverse Effects: Ipratropium

A

dry mouth
urinary retention
infection
sinusitis
bronchitis

28
Q

Clinical Pearls: Ipratropium

A

used in combo with albuterol for asthma exacerbation treatment

may mix in same nebulizer with albuterol

should not be used as first-line therapy; should be added to SABA therapy for severe exacerbations

29
Q

Drug Class: Ipratropium/Albuterol

30
Q

Brand Name: Ipratropium/Albuterol

A

Combivent Respimat
DuoNeb

31
Q

Dosage Form: Ipratropium/Albuterol

A

MDI (Respimat)
Nebulizer Solution (DuoNeb)

32
Q

Age Group Dosing: Ipratropium/Albuterol

33
Q

Adverse Effects: Ipratropium/Albuterol

A

see individual products

34
Q

Clinical Pearls: Ipratropium/Albuterol

A

may be used for up to 3 hours in initial management of severe exacerbations (nebulizer)

35
Q

Drug Class: Methylprednisolone

A

Systemic Corticosteroids

36
Q

Dosage Form: Methylprednisolone

A

Tablets
Oral Liquid

37
Q

Age Group Dosing: Methylprednisolone

38
Q

Drug Class: Prednisolone

A

Systemic Corticosteroids

39
Q

Dosage From: Predisolone

A

Tablets
Oral Liquid

40
Q

Age Group Dosing: Prednisolone

41
Q

Drug Class: Prednisone

A

Systemic Corticosteroids

42
Q

Dosage Form: Prednisone

A

Tablets
Oral Liquids

43
Q

Age Group Dosing: Prednisone

44
Q

Drug Class: Dexamethasone

A

Systemic Corticosteroids

45
Q

Dosage Form: Dexamethasone

A

Oral Liquid
Tablets
Injection

46
Q

Age Group Dosing: Dexamethasone

47
Q

Drug Class: Methylprednisolone Acetate

A

Systemic Corticosteroids

48
Q

Dosage Form: Methylprednisolone Acetate

A

Repository Injection

49
Q

Age Group Dosing: Methylprednisolone Acetate

50
Q

Adverse Effects: Systemic Corticosteroids

A

hyperglycemia
increased appetite
fluid retention
demargination of WBCs
psychiatric disturbances

51
Q

Clinical Pearls: Systemic Corticosteroids

A

CI: systemic fungal infections, administration of live vaccine if immunocompromised

DI: Warfarin INR increase, decreased efficacy of inactivated vaccines

may be used with ICS if patient is already taking ICS before hospitalization

may also be used for chronic therapy in both asthma and COPD only in severe stages

bursts effective for establishing control when intiating therapy or during period of gradual deterioration

injection may be used in place of burst if adherence is an issue or patient is vomiting

52
Q

Epinephrine Injection

A

no proven advantage of systemic therapy over aerosol

indicated in addition to standard therapy for acute asthma associated with anaphylaxis and/or angioedema

53
Q

Terbutaline Injection

A

no proven advantage of systemic therapy over aerosol

54
Q

Magnesium sulfate IV

A

AE: flushing, hypotension, vasodilation

CI: heart block, caution in renal dysfunction

Consider if patient remains in life-threatening exacerbation after 1 hour of therapy

PHRM 825 (8 decks)

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