Long-Term Control Medications in Asthma and COPD Flashcards
Class: Beclomethasone
inhaled corticosteroid
Brand Name: Beclomethasone
QVAR
Dosage Form: Beclomethasone
Redihaler (MDI)
Age Groups: Beclomethasone
5-11 yo, adults
Class: Budesonide
inhaled corticosteroids (ics)
Brand Name: Budesonide
Pulmicort
Dosage Form: Budesonide
Flexhaler
Age Groups: Budesonide
5-11 yo, adults
Class: Budesonide Solution
inhaled corticosteroids
Brand Name: Budesonide Solution
Pulmicort Respules
Dosage Form: Budesonide Solution
Nebulizer Solution
Age Group Dosing: Budesonide Solution
0-4, 5-11 yo
Class: Ciclesonide
inhaled corticosteroid
Brand Name: Ciclesonide
Alvesco
Dosage Form: Ciclesonide
HFA
Age Group Dosing: Ciclesonide
5-11 yo, adults
Class: Fluticasone Propionate
inhaled coritcosteroid
Brand Name: Fluticasone Propionate
Flovent (HFA, DPI), ArmonAir (Aerosol Powder Inhaler)
Dosage Form: Fluticasone Propionate
HFA, DPI, Aerosol Powder Inhaler
Age Group Dosing: Fluticasone Propionate
HFA ( 4+ yo)
DPI (4+ yo)
MDPI (adult only)
Class: Fluticasone Furoate
inhaled corticosteroids
Brand Name: Fluticasone Furoate
Arnuity Ellipta
Dosage Form: Fluticasone Furoate
Ellipta
Age Group Dosing: Fluticasone Furoate
5-11 yo, adults
Class: Mometasone
inhaled corticosteroid
Brand Name: Mometasone
Asmanex
Dosage Form: Mometasone
HFA, Twisthaler
Age Group Dosing: Mometasone
HFA: 5-11 yo, adult
Twisthaler: 4-11 yo, adult
Adverse Effects: ICS
oral thrush (candidiasis)
cough
dysphonia
Education Tips: ICS
patients should rinse their mouth and spit after use to prevent oral thrust
ICS are most effective long-term control therapy for asthma (improve QOL, increase lung function, and reduce risk of exacerbations)
Titrate to lowest effective dose: see low, medium, and high dose conversion tables
Pulmicort Respules should use Jet Nebulizer and should not be mixed with other nebulizer medications
High doses increase the risk for systemic side effects
Uses: ICS
prevent and control inflammation
Class: Arformoterol Tartrate
long acting beta agonist (LABA)
Brand Name: Arformoterol Tartrate
Brovana
Dosage Form: Arformoterol Tartrate
Nebulizing Solution
Age Group Dosing: Arformoterol Tartrate
Adults (COPD only)
Class: Formoterol
long acting beta agonist (LABA)
Brand Name: Formoterol
Perforomist
Dosage Form: Formoterol
Nebulizer Solution
Age Group Dosing: Formoterol
Adults (COPD only unless used in combination with ICS)
Class: Indacaterol
long acting beta agonist (LABA)
Brand Name: Indacaterol
Arcapta Neohaler
Dosage Form: Indacaterol
Neohaler
Age Group Dosing: Indacaterol
Adults (COPD only)
Class: Olodaterol
long acting beta agonist (LABA)
Brand Name: Olodaterol
Striverdi Respimat
Dosage Form: Olodaterol
Respimat
Age Group Dosing: Olodaterol
Adult (COPD only)
Class: Salmeterol
long acting beta agonist (LABA)
Brand Name: Salmeterol
Serevent
Dosage Form: Salmeterol
Diskus
Age Group Dosing: Salmeterol
4+ yo, adults
Adverse Effect: Long Acting Beta Agonists (LABA)
tachycardia
headache
tremor
hypokalemia
Education Tips: Long Acting Beta Agonists
Boxed Warning: increased risk of asthma related death for all monotherapy. LABA should not be used alone for asthma management
Boxed Warning: increasing hospitalizations in pediatric and adolescent patients
Prolonged QT seen with intentional overdoses
Not for acute symptoms
May be helpful for exercise induced bronchospasm
Formoterol and indacaterol capsules should not be taken orally
Pediatric Considerations: most children > 4 yo cannot provide sufficient inspiratory flow for adequate lung delivery with a DPI
Use: Long Acting Beta Agonist (LABA)
increase cAMP
bronchial smooth muscle relaxation and inhibit hypersensitivity mediators from mast cells (histamine and leukotrienes)
Class: Aclindium
long acting antimuscarinics (LAMA)
Brand Name: Aclindinium
Turdorza Pressair
Dosage From: Aclindinium
DPI
Age Group Dosing: Aclindinium
Adult (COPD only)
Class: Glycopyrrolate
long acting antimuscarinics (LAMA)
Brand Name: Glycopyrrolate
Seebri Neohaler
Dosage Form: Glycopyrrolate
DPI, Nebulizing Solution
Age Group Dosing: Glycopyrrolate
Adult (COPD Only)
Class: Revefenacin
long acting antimuscarinics (LAMA)
Brand Name: Revefenacin
Yupelri
Dosage From: Revefenacin
Nebulizing solution
Age Group Dosing: Revefenacin
Adult (COPD only)
Class: Tiotropium
long acting antimuscarinics (LAMA)
Brand Name: Tiotropium
spirivia
Dosage From: Tiotropium
HandiHaler
Respimat
Age Group Dosing: Tiotropium
Handihaler: Adult (COPD only)
Respimat: 6+ yo