Repsonding To The Environment Flashcards
Some neurones are myelinated. What does this mean?
They have a myelin sheath, which is an electrical insulator. It is made of a Schwann cell. Between these cells, there are tiny patches of bare membrane called the nodes of Ranvier. Sodium channels are concentrated here. Depolarisation takes place here.
3 factors that affect the speed of conduction of action potentials
Myelination
Axon diameter
Temperature
How are impulses sent along a myelinated neurone
Myelin sheath made up of Schwann cell, between these cells are tiny patches of bare membrane called nodes of Ranvier. Sodium ion channels are concentrated here. Depolarisation only happens at nodes. The neurones cytoplasm conducts enough electrical charge to depolarise next node, so impulse jumps from node to node. Called saltatory conduction, very fast
How are impulses sent in a non-myelinated neurone
The impulse travels as a wave along the whole length of the axon membrane. It is slower than saltatory conduction
How does axon diameter affect the speed on conduction
Action potentials are conducted quicker along axons with bigger diameters as there is less resistance to the flow of ions than in the cytoplasm of a smaller axon. With less resistance, depolarisation reaches other parts of the neurone cell membrane quicker
How does temperature affect the speed on conduction
Speed of conduction increases as the temp increases as ions diffuse faster as they have more energy to move. The speed only increases up to around 40c, after this the proteins begin to denature and speed decreases
What is a synapse
A junction between a neurone and the next cell
The tiny gap between the cells at a synapse is called….
Synaptic cleft
Acetylcholine is a what? What does it do?
Neurotransmitter
It transmits the nerve impulse across a cholinergic synapse
What is a neuromuscular junction
A synapse between a motor neurone and a muscle cell
What do neuromuscular junctions use
Neurotransmitter acetylcholine which binds to cholinergic receptors called nicotinic cholinergic receptors. They work in the same way as the cholinergic synapse but…. The post synaptic membrane has lots of folds that form clefts. These clefts store the enzyme that breaks down acetylcholine. The membrane also has more receptors. When motor neurone fires an action potential, always triggers a response in muscle cell, this isn’t always the case for a synapse between 2 neurones
Neurotransmitters are either ……….. or ………….
Excitatory or inhibitory
Excitatory neurotransmitters info
Depolarise the post synaptic membrane making it fire an action potential of threshold reached. Eg acetylcholine binds to cholinergic receptors to cause an action potential in post synaptic membrane
Inhibitory neurotransmitters info
Hyperpolarise the post synaptic membrane (make the potential difference more negative), preventing it from firing an action potential. Eg GABA, when it binds to its receptors it causes potassium ion channels to open on the post synaptic membrane, hyperpolarising the neurone
What happens if the stimulus is weak
Only a small amount of neurotransmitter will be released from neurone into synaptic cleft. This might not be enough to excite the post synaptic membrane to the threshold potential and stimulate an action potential
What is summation
Where the effect of neurotransmitter released from many neurones (or one neurone that’s stimulated a lot in a short period of time) is added together
What are the 2 types of summation
Spatial and temporal
What is spatial summation
Many neurones connect to 1 neurone. The small amount of neurotransmitter released from each of these neurones can be enough altogether to reach the threshold potential in the post synaptic neurone and trigger an action potential. OR If some neurones release an inhibitory neurotransmitter then the total effect of all the neurotransmitters might be no action potential
What is temporal summation
Where 2 or more nerve impulses arrive in quick succession from the same pre synaptic neurone. Makes an action potential more likely because more neurotransmitter is released into the synaptic cleft
What is the function of summation at synapses
It means that synapses accurately process info
5 examples of how drugs can affect synaptic transmission
Some drugs are the same shape
Some block receptors
Some inhibit the enzyme that breaks down neurotransmitters
Some stimulate the release of neurotransmitter
Some inhibit the release of neurotransmitter
How do drugs that are the same shape affect synaptic transmission
Same shape as neurotransmitters so they mimic their action at receptors. Means more receptors are activated.
How do drugs that block receptors affect synaptic transmission
They block receptors so they can’t be activated by neurotransmitters. Means fewer receptors can be activated
How do drugs that inhibit the enzyme that breaks down neurotransmitters affect synaptic transmission
Inhibit the enzyme so there are more neurotransmitters in the synaptic cleft to bind to receptors and they’re there for longer
How do drugs that stimulate the release of neurotransmitter affect synaptic transmission
Stimulate the release of neurotransmitter from the presynaptic neurone so more receptors are activated
How do drugs that inhibit the release of neurotransmitter affect synaptic transmission
Inhibit the release of neurotransmitter from the presynaptic neurone so fewer receptors are activated
What is a stimulus
Any change in the internal or external environment of an organism
Receptors detect….
Stimuli
They can be cells or proteins on cell surface membranes
Organisms increase their chance of survival by responding to changes in their….
Internal and external Environment
What are effectors
Cells that bring about a response to a stimulus, to produce an effect. Effectors include muscle cells and cells found in glands like the pancreas
How do receptors communicate with effectors
Via the nervous system, the hormonal system or both
The nervous system sends info as…..
Electrical impulses
The nervous system is made up of a ……….
Complex network of cells called neurones
What are the 3 main types of neurone
Sensory neurone
Relay neurone
Motor neurone
What do sensory neurones do
Transmit electrical impulses from receptors to the central nervous system
What do motor neurones do
Transmit electrical impulses from the CNS to effectors
What do relay neurones do
Transmit electrical impulses between the sensory and motor neurones