Homeostasis Flashcards

0
Q

What do homeostatic systems do? What do they involve?

A

They detect a change and respond by negative feedback

They involve receptors, a communication system and effectors

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1
Q

What is homeostasis

A

The maintenance of a constant internal environment

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2
Q

Why does homeostasis involve more than 1 negative feedback mechanism

A

Having more than 1 gives more control over changes in the internal environment. Having multiple mechanisms means you can actively increase or decrease a level so it returns to normal

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3
Q

What would happen if you only had one negative feedback mechanism

A

All you could do is turn it on or turn it off. You would only be able to actively change a level in one direction so it returns to normal. Only one mechanism means a slower response and less control

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4
Q

What does a positive feedback mechanism do

A

Amplify a change from the normal level. The effectors respond to further increase the level away from the normal level

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5
Q

what are positive feedback mechanisms useful for? Example.

A

To rapidly activate something. Eg blood clot after injury…

Platelets activated, release chemical which triggers more platelets to be activated, and so on

Platelets very quickly form blood clot at injury site

Process ends with negative feedback when body detects the blood clot has been formed

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6
Q

Why isn’t positive feedback involved in homeostasis

A

Because it doesn’t keep your internal environment constant

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7
Q

Examples of ectotherms

A

Reptiles

Fish

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8
Q

Examples of endotherms

A

Mammals

Birds

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9
Q

How do ectotherms control their body temp

A

They can’t control their body temp internally, instead control their temp by changing their behaviour (eg reptiles laying in sun)

Their internal temp depends on the external temp

Their activity level depends on the external temp, they’re more active at higher temps

Have a variable metabolic rate and generate little heat themselves

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10
Q

How do endotherms control their body temp

A

Control temp internally by homeostasis. Can also control their temp by behaviour (eg finding shade)

Their internal temp is less affected by external temp, they can be active at any temp

Their activity level is largely independent of external temp, can be active at any temp

Have a constantly high metabolic rate, generate lots of heat from metabolic reactions

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11
Q

Body temp in mammals is maintained at a constant level by a part of the brain called the…

A

hypothalamus

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12
Q

What is the hypothalamus and what is its role

A

A part of the brain which maintains body temp at a constant level in mammals

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13
Q

How does the hypothalamus work

A

It receives info from both internal and external temp from thermoreceptors

Info about internal temp comes from thermoreceptors in the hypothalamus that detect blood temp

Info about the external temp comes from thermoreceptors in the skin which detect skin temp

Thermoreceptors send impulses along sensory neurones to hypothalamus, which sends impulses along motor neurones to effectors (muscle and glands)

The neurones are part of the autonomic nervous system, so is done unconsciously

The effectors restore body temp back to normal

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14
Q

What does FSH do

A

Stimulates the development of follicles in the ovaries. Stimulates the follicles to produce oestrogen

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15
Q

What is a follicle

A

An egg and its surrounding protective cells. Developed in the ovary

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16
Q

What is ovulation

A

The release of an egg

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17
Q

What does LH do

A

Causes ovulation and stimulates the ovaries to produce progesterone from corpus luteum

18
Q

What does oestrogen do

A

Causes the rebuilding of the uterus lining after menstruation, stimulates the pituitary gland to produce LH and FSH. Can also inhibit both LH and FSH

19
Q

What does progesterone do

A

Maintains the lining of the uterus in preparation to receive the fertilised egg. It inhibits the production of FSH and LH from the pituitary gland

20
Q

Where is FSH secreted from

A

Pituitary gland

21
Q

Where is LH secreted from

A

Pituitary gland

22
Q

Where is oestrogen secreted from

A

Ovaries

23
Q

Where is progesterone secreted from

A

The corpus luteum in the ovaries

24
Q

What is the normal concentration of glucose in the blood

A

90 mg per 100cm3 of blood

25
Q

What monitors glucose concentration in blood

A

Cells in pancreas

26
Q

When does the blood glucose conc increase

A

After eating food containing carbohydrate

27
Q

When does the blood glucose conc decrease

A

After exercise, as more glucose used in respiration to release energy

28
Q

The hormonal system controls blood glucose conc using which 2 hormones?

A

Insulin and glucagon

29
Q

Which system controls the blood glucose conc

A

Hormonal system

30
Q

Insulin and glucagon are secreted by…

A

Clusters of cells in the pancreas called the islets of Langerhans

31
Q

What are the islets of Langerhans

A

Cluster of cells in pancreas which secrete insulin and glucagon

32
Q

What do beta cells do

A

Secrete insulin into the blood

33
Q

What do alpha cells do

A

Secrete glucagon into blood

34
Q

What is another name for liver cells

A

Hepatocytes

35
Q

Role of adrenaline in controlling blood glucose conc

A

Adrenaline is a hormone secreted from the adrenal glands. Secreted when there is a low conc of glucose in blood. It binds to receptors in cell membrane of liver cells and activates glycogenolysis. It inhibits glycogenesis. It also activates glucagon secretion and inhibits insulin secretion which increases glucose conc. Adrenaline gets the body ready for action by making more glucose available for muscles to respire.

36
Q

What is glycogenolysis

A

The breakdown of glycogen to glucose

37
Q

What is glycogenesis

A

The synthesis of glycogen from glucose

38
Q

Diabetes occurs when…

A

Blood glucose conc is not controlled

39
Q

What is diabetes mellitus

A

A condition where blood glucose conc can’t be controlled properly. Two types, type 1 and type 2.

40
Q

What is type 1 diabetes

A

The beta cells in the islets of Langerhans don’t produce insulin. After eating, the blood glucose level rises and stays high, called hyperglycaemia, can result in death. The kidneys can’t reabsorb all the glucose so some is excreted in urine. Can be treated by regular injections of insulin, this has to be carefully controlled as too much can produce a dangerous drop in blood glucose levels, called hypoglycaemia. Eating regularly and controlling simple carb intake helps avoid sudden rise in glucose

41
Q

What is type 2 diabetes

A

Usually acquired later in life then type 1, often linked to obesity. Occurs when beta cells don’t produce enough insulin or when the body’s cells don’t respond properly to insulin. Cells don’t respond properly because the insulin receptors on their membranes don’t work properly, so the cells don’t take up enough glucose. Means the blood glucose conc is higher than normal. It can be treated by controlling simple carb intake and losing weight. Glucose-lowering tablets can be taken if diet and weight loss can’t control it.

42
Q

When insulin binds to receptors on liver cells it forms glycogen which lowers the glucose conc in liver cells. how?

A

When glycogen formed the glucose conc falls below that in blood

Creates diffusion gradient

Glucose enters the cells, leaves the blood via facilitated diffusion