Reproductive Immunology Flashcards

1
Q

Which immune cells are present at the implantation site?

A

NK cells (70%)
Macrophages (20%)
T-cells (10%)

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2
Q

Cytokine profile according to pregnancy trimester

A

1st trimester: inflammation (Th1) essential for implantation
2nd: anti-inflammation (Th2) essential for placentation
3rd: inflammation (Th1) essential for parturition

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3
Q

___ cells prevent inflammation allowing implantation

A

Dendritic

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4
Q

Dendritic cells down-regulate ___ and up-regulate to prepare the endometrium for implantation

A

MUC-16 (down)

CD 44 (up)

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