Reproductive Axis Flashcards

1
Q

What hormone is released from the posterior pituitary and acts on the uterus?

A

Oxytocin

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2
Q

What type of receptor does Oxytocin bind to?

A

Gq alpha

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3
Q

What action does oxytocin binding cause?

A

Contraction

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4
Q

What type of receptor does GnRH bind?

A

Gq

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5
Q

What type of receptor does FSH and LH bind?

A

Gs

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6
Q

What three locations does LH act upon in women?

A

Thecal cell, Placenta, Corpus Luteum

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7
Q

What does the thecal cell produce?

A

Testosterone

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8
Q

What does testosterone from the thecal cell cause?

A

Alters transcription and causes feminization.

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9
Q

What does the placenta secrete?

A

Chorionic gonadotropin

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10
Q

What type of receptor does Chorionic gonadotropin bind?

A

Gs alpha

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11
Q

What is the function of Chorionic gonadotropin?

A

CL maintenance

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12
Q

What does the Corpus Luteum secrete?

A

Progesterone

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13
Q

Where does Progesterone from the Corpus Luteum act?

A

Alters transcription and acts at the uterus for pregnancy

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14
Q

What two locations does FSH act on in women?

A

Ovary (follicle) and Granulosa cell

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15
Q

What is produced from the ovary when FSH is released?

A

Ovum which aids in reproduction

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16
Q

What is produced from the Granulosa cell when FSH is released?

A

Inhibin and estradiol

17
Q

What are the functions of Inhibin and estradiol in women?

A

Reduce FSH secretion

18
Q

What two locations does LH act on in men?

A

Leydig and Sertoli cell

19
Q

What do Sertoli cells release (LH) and what does it do?

A

Inhibin which reduces FSH secretion

20
Q

What do Leydig cells release and what does it do?

A

Testosterone. It alters transcription and causes masculinization.

21
Q

What locations does FSH act on in men?

A

Sertoli Cell

22
Q

What does the Sertoli cell release in response to FSH and what does it do?

A

Sperm, reproduction