Reproductive Flashcards
If you have SRY you will get rid of mullein or wolffian?
get rid of malarian.
What stores sperm?
Ampulla
What contains sperm but semen does not travel through them?
Seminal vesicle and bulbourethral glands
What is the order that sperm travels from the seminiferous tubules?
Seminiferous tubules, tubuli recti, rete testis, ductus efferentes, ductus epididymis
What are the components of the testes
Seminiferous tubules (sertoli cells, spermatogonia) interstitial (leydig) cells
Intratesticular ducts
Tubuli recti, rete testis, ductuli efferentes
Excretory ducts
Ductus epididymis, vas deferens, urethra
Accessory glands
seminal vesicles, cowpers glands (bulbourethral)
Describe the life of the spermatogonia
Arises from the basement membrane, forms two daughter cells (mitosis), then the primary spermatocyte undergoes a first meiotic division forming two secondary spermatocytes (46 each) then these undergo a 2nd meiotic division to SPERMATIDS with 23 chromosomes each.
At what point are the cells like any other cells in our body?
secondary spermatocytes.
At what point does crossover occur?
Prophase, the primary spermatocyte doubles, crosses over, and forms secondary spermatocytes (46 each)
What propels the sperm forward?
Microtubules, the acrosome is the tip of the spear
What does LH do?
Stimulates LEYDIG cells to produce TESTOSTERONE
What does FSH do?
Stimulates SERTOLI cells to make SPERM
What is testosterone important for?
to stimulate SERTOLI cells (FSH also stimulates sertoli cells); also, SERTOLI CELLS secrete inhibin which stimulates hypothalamus
In the Sertoli cell, Testosterone binds to what?
ABP, androgen binding protein
What are the 4 stages of an ovarian follicle
Primodial follicle, primary follicle, secondary follicle, graffian follicle
Primary follicle
Granulosa cells emerge (has a basal lamina, oocyte
Secondary follicle
Theca cells outside the granulosa cells,
Graffian follicle
Theca externa, theca interna (secretes sex hormones), Antrum, OOcyte
What causes rupture?
surge of collagenase causes weekend theca externa
What causes ovulation?
Surge of LH!
What does granulosa cells make?
androgens and progesterone, which is turned to estrogens by aromatase (theca cells lack aromatase)
What does the theca intena make?
cholesterol -> androgens which diffuse over to the granulosa cells though the basement membrane and aromatase turns androgens to estrogens.