Reproductive Flashcards

1
Q

If you have SRY you will get rid of mullein or wolffian?

A

get rid of malarian.

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2
Q

What stores sperm?

A

Ampulla

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3
Q

What contains sperm but semen does not travel through them?

A

Seminal vesicle and bulbourethral glands

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4
Q

What is the order that sperm travels from the seminiferous tubules?

A

Seminiferous tubules, tubuli recti, rete testis, ductus efferentes, ductus epididymis

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5
Q

What are the components of the testes

A

Seminiferous tubules (sertoli cells, spermatogonia) interstitial (leydig) cells

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6
Q

Intratesticular ducts

A

Tubuli recti, rete testis, ductuli efferentes

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7
Q

Excretory ducts

A

Ductus epididymis, vas deferens, urethra

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8
Q

Accessory glands

A

seminal vesicles, cowpers glands (bulbourethral)

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9
Q

Describe the life of the spermatogonia

A

Arises from the basement membrane, forms two daughter cells (mitosis), then the primary spermatocyte undergoes a first meiotic division forming two secondary spermatocytes (46 each) then these undergo a 2nd meiotic division to SPERMATIDS with 23 chromosomes each.

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10
Q

At what point are the cells like any other cells in our body?

A

secondary spermatocytes.

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11
Q

At what point does crossover occur?

A

Prophase, the primary spermatocyte doubles, crosses over, and forms secondary spermatocytes (46 each)

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12
Q

What propels the sperm forward?

A

Microtubules, the acrosome is the tip of the spear

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13
Q

What does LH do?

A

Stimulates LEYDIG cells to produce TESTOSTERONE

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14
Q

What does FSH do?

A

Stimulates SERTOLI cells to make SPERM

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15
Q

What is testosterone important for?

A

to stimulate SERTOLI cells (FSH also stimulates sertoli cells); also, SERTOLI CELLS secrete inhibin which stimulates hypothalamus

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16
Q

In the Sertoli cell, Testosterone binds to what?

A

ABP, androgen binding protein

17
Q

What are the 4 stages of an ovarian follicle

A

Primodial follicle, primary follicle, secondary follicle, graffian follicle

18
Q

Primary follicle

A

Granulosa cells emerge (has a basal lamina, oocyte

19
Q

Secondary follicle

A

Theca cells outside the granulosa cells,

20
Q

Graffian follicle

A

Theca externa, theca interna (secretes sex hormones), Antrum, OOcyte

21
Q

What causes rupture?

A

surge of collagenase causes weekend theca externa

22
Q

What causes ovulation?

A

Surge of LH!

23
Q

What does granulosa cells make?

A

androgens and progesterone, which is turned to estrogens by aromatase (theca cells lack aromatase)

24
Q

What does the theca intena make?

A

cholesterol -> androgens which diffuse over to the granulosa cells though the basement membrane and aromatase turns androgens to estrogens.

25
binding of LH to LH receptors on the THECAL CELL do what?
increase androgen synthesis
26
What does stimulation of FSH receptors cause?
GRANULOSA CELLS convert androgens to estrogens
27
What are the three forms of estrogen?
Estrodiol (most common), estrone, estriol
28
What are the two phases of menstruation?
follicular phase (FSH) and luteal phase (LH)
29
After ovulation what forms?
Corpus luteum (then scar is corpus albicans)
30
What does the corpus luteum secrete?
PROGESTERONE. Progesterone keeps the endometrium waiting... once progesterone drops, the period occurs.
31
What is the follicular vs. luteal phase?
PROLIFERATIVE= FOLLICULAR | SECRETORY=LUTEAL
32
At midcycle estrogen becomes a positive feedback and this causes what to happen?
LH and FSH spike and this causes ovulation.
33
What produces inhibit in the woman?
granulosa cells
34
High levels of estrogen cause what?
LH spike induces ovulation and development of corpus luteum. LUTEUM PRODUCES PROGESTERONE AND ESTROGEN! which does negative feedback on the hypothalamus to inhibit GnRH from the hypothalamus.
35
What causes menstraution?
when estrogen and progesterone tailor down due to LH falling and progesterone not being produced.
36
Where do androgens in the female come from?
adrenal cortex
37
What is the chorionic villi?
produced by the egg, goes into the endometrium to produce more surface area, produces HCG
38
What hormone stimulates progesterone production?
LH stimulates progesterone production after ovulation.
39
Newborn has high levels of what?
FSH and also LH to a lesser extent. at menopause, FSH and LH keep climbing bc they are looking for a good follicle and there is none, so theres no negative feedback. LH surges in the reproductive years.