Reproduction Flashcards
What characteristcs do all mammals share?
Mammary Glands
Three Bones in Middle Ear
One bone in Lower Jaw
Fur/Hair
Sebaceous (oil) and Sudoriferous (Sweat) Glands
Heterodont Dentification (different teeth)
Diploid (2n)
share 2 copies of each chromosomes
autosomal cells
Haploid (n)
one copy of each chromosome
germ cells
The Stages of Cell Cycle
G1 , S, G2, M
G1, S and G2 are known as…
interphase, the longest part of cell cycle
Cells that do NOT divide are in the…
G0 phase, they just perform a function and do not divide
During interphase, chromosomes are not visible, they are in the form of….because…
chromatin so the DNA is available for transcription
G1 Stage
cells create organelles for energy and protein production but also grow
To go from G1 to S phase…
must pass through restriction point where it checks from proper complement of DNA
S Stage
cell replicates its genetic material for each daughter cell
Each chromosome is now two identical chromatids
NUMBER OF CHROMOSOMES IS SAME, JUST CHROMATIDS IS DOUBLED
Chromatid
made during S phase with condensing and replication of DNA to be bound at centromere
G2 Phase
cell has twice as much DNA now than in G1
another checkpoint to make sure there are enough organelles/cytoplasm for division and that DNA has been properly replicated
M Phase
mitosis and cytokinesis
4 stages: prophase, metaphase, anaphase and telophase
cytokinesis is the splitting into two cells
If there has been any damage to the DNA the cell cycle goes into arrest until DNA is repaired, the main protein involved in this process is….
p53
Cyclins and Cyclin Dependent kinases (CDKs)
molecules responsible for cell cycle
CDK is activated by specific cyclins to activate and phosphorylate transcription factors to transcript genes for next stage of cell cycle
Most common mutation to cause cancer…
mutation of p53 gene, the TP53
Cancer
uncontrolled cell division caused by allowing DNA to not properly be replicated and produce cells growths known as tumors
Metastasis
invasion of cancerous cells to other parts of the body
Mitosis occurs in….
somatic cells, those not involved in sexual reproduction
Prophase
chromatin condenses to chromosomes
centriole pairs separate and move towards opposite poles of the cell to the centrosome
Nuclear membrane goes away
centrioles prepare spindle fibers which can either anchor the centriole to the cellular membrane or attach to centromere of chromosomes via kinetochores
Centriole
produce spindle fibers (made of microtubules) to attach to cell membrane or chromosomes
Centrosome
region where centrioles are kept
Spindle fibers
come from centrioles, made of microtubuleles
Asters
spindle fibers which anchor centrioles to the cell membrane