Reproduction Flashcards
What are autosomal cells?
Cells that do not have sex chromosomes
What is interphase?
Longest phase of the cell cycle which encompasses G1, S, and G2
What is G0 stage?
Stage/phase in which the cell is serving its function and not getting ready to divide
What occurs in G1 phase?
Cells create organelles for energy and protein synthesis, and grow in size.
What occurs in G1/S restriction point?
Makes sure DNA is ready/ repairs DNA for S phase
What occurs in the S Phase?
Cell replicates itself so daughter cells have identical copies
What exactly counts as a chromosome?
A single chromatid before S phase or a pair of chromatids attached at the centromere after S phase. Still the same ploidy, simply double the amount of chromatids.
What occurs in G2 + G2/M restriction point?
Makes sure that there are enough organelles and cytoplasm for both cells
General Steps of Mitosis?
Prophase, Metaphase, Anaphase, Telophase… Cytokinesis
What is p53?
A protein that largely regulates the cell cycle and therefore suppresses tumors. It is affected by a gene called TP53
2 Molecules involved with the Cell Cycle that start with a C and what do they do?
Cyclin and Cyclin Dependent Kinases (CDK). Cyclin binds to CDK which phosphorylates transcription factors that promote transcription for the next stage.
What is cancer?
The division of unhealthy/damaged cells. Rapid and uncontrolled division can lead to tumors– abnormal growths of tissue.
What is the spread of cancer to other parts of the body called?
Metastasis
What is a somatic cell?
Cell not involved in reproduction
What occurs in Prophase of Mitosis?
Chromatin is condensed to chromosomes. Nucleus disappears. Centriole pairs move towards opposite poles and as centrosomes they create and spread spindle fibers made of microtubules. and attach to kinetochores at the centromere.
(Picture)
What is an aster?
Centrosome produced mitotic spindle that attaches and anchors to the cell membrane.
What occurs during Metaphase?
Kinetochore and spindle fibers interact causing chromosomes to align at the metaphase plate.
(Picture)
What happens during Anaphase?
Sister chromatids are pulled to opposite poles by spindle fibers and the shortening of kinetochore fibers.
What happens during Telophase and Cytokinesis?
“Reverse of prophase.” Spindle apparatus disappears and nucleus begins to form. Chromosomes revert back to chromatin and the splitting of the cytoplasm begins.
Do somatic cells undergo Meiosis?
No, only reproductive/ gametocytes undergo meiosis.
What is Reductional Division?
Cell division in which the ploidy is reduced (2n–>n)
What is Equal Division?
Ploidy remains the same (n–>n)
*Some differences between Mitosis and Meiosis:
Mitosis is one round of replication and one round of division. Meiosis is one round of replication and two rounds of division. Meiosis I is an example of reductional division while Meiosis II is an example of equal division.