Reproduction 2 - Female Reproductive System Flashcards

1
Q

What are some of the female reproductive organs?

A
  • Uterus
  • Fallopian tubes
  • Vagina
  • Ovaries
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2
Q

Is the duct system of the female reproductive tract short or long?

A

The duct system for the transference of gametes is short, and leads from the ovaries to the uterus, where implantation and development of the zygote occurs.

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3
Q

Where does implantation and development of the zygote occur?

A

ampulla of the fallopian tube

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4
Q

What are the 3 structures of the birth canal?

A

Cervix

Vagina

Vulva

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5
Q

What are the 3 layers of the uterus?

A

Perimetrium – outer serous coat, made of peritoneum supported by thin layer of connective tissue

Myometrium – middle muscular coat of smooth muscle which gradually becomes distended during pregnanct, main branches of blood vessels and nerves are located here

Endometrium – inner mucous coat

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6
Q

In what layer of the uterus are the main blood vessels and nerves located?

A

Myometrium

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7
Q

As pregnancy advances, how can the uterus be split physiologically?

A

As pregnancy advances the uterus physiologically has an ‘upper’ segment and a ‘lower segment’

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8
Q

What area of the uterine body does the lower segment develop from?

A

Isthmus

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9
Q

When a caesarean delivery is done which part of the uterus is opened to deliver the baby?

A
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10
Q

What area develops into the lower segment of the uterus during pregnancy?

A

The area between the cervix and uterus develops into the lower segment

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11
Q

What kind of incision is used for caesarean section?

A

When a caesarean section is required the uterus is opened at the lower segment with a transverse incision for delivery of the baby (Pfannenstiel)

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12
Q

Describe the normal position of the uterus?

A

The normal position of the uterus is ‘anteflexed’ and ‘anteverted’

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13
Q

What is the opposite of anteverted and anteflexed?

A

Retroverted and retroflexed

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14
Q

What could happen if the position of the uterus is very retroverted and retroflexed, particularly in early pregnancy? Think of the position of the other organs…

A

Bladder or rectum problems

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15
Q

At any surgical management of miscarriage why might it be important to know prior to instrumentation of the uterine cavity whether the uterus is anteverted or retroverted?

A

Could perforate the uterus

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16
Q

What peritoneal spaces are around the vagina?

A

rectouterine and uterovesical peritoneal spaces

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17
Q

What are the fornices of the vagina?

A

Definition – recess around the protruding cervix

1) Anterior – fundus of urinary bladder and urethra
2) Lateral – levator ani, visceral pelvic fascia and ureters
3) Posterior – anal canal, rectum and recto-uterine pouch

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18
Q

How many fornices of the vagina are they?

A

3

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19
Q

What forms the following fornices of the vagina:

  • anterior
  • lateral
  • posterior
A

1) Anterior – fundus of urinary bladder and urethra
2) Lateral – levator ani, visceral pelvic fascia and ureters
3) Posterior – anal canal, rectum and recto-uterine pouch

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20
Q

Through which vaginal fornix you can access the rectouterine pouch? What is the clinical significance of this?

A

Posterior fornix

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21
Q

What are the ligamentous attachments that anchors the uterus and cervix in position?

A
  • Ligament of ovary
  • Suspensory ligament of ovary
  • Round ligament of uterus
  • Broad ligament
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22
Q

Which ligament (part of the pelvic fascia, which is one of the main supports of the uterus) is called the cardinal ligament of the uterus?

A

Broad ligament of uterus

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23
Q

Apart from pelvic fascia, what other structure in the pelvis is also an important support of the uterus?

A

Muscles of pelvic floor (perineal muscles)

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24
Q

What is the difference between the cervix and the uterus in terms of movement?

A

In the pelvis the cervix is a fixed structure, supported by strong ligaments to prevent movement. The uterus is supported, but has ability to move, especially when increasing in size during pregnancy.

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25
Q

What are the 4 parts of the uterine tubes?

A

1) Infundibulum
2) Ampulla
3) Isthmus
4) Intramural or uterine part

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26
Q

What part of the uterine tube is the longest and widest?

A

Ampulla

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27
Q

Fertilisation occurs in which part of the uterine tube?

A

Ampulla

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28
Q

What is meant by tubal (ectopic) pregnancy?

A

Implantation occurs in mucosa of uterine tube (most commonly ampulla) due to blastocyst failing to reach the uterus

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29
Q

What might a cornual ectopic pregnancy be?

A

Implantation occurs in the cavity of a rudimentary horn of the uterus

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30
Q

Where are the ovaries located?

A

The ovaries are located in the lateral walls of the pelvis, supported by 2 ligaments.

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31
Q

What happens to the ovaries after menopause?

A

After menopause they become atrophied and fibrous

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32
Q

What are the two ligaments associated with the ovary?

A
  • From uterus to ovary
    • Ligament of ovary
  • Ovary to lateral pelvic wall
    • Suspensory ligament
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33
Q

What does the ligament of ovary connect?

A

Uterus to ovary

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34
Q

What does the suspensory ligament connect?

A

Ovary to lateral pelvic wall

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35
Q

What are the 2 major branches from the aorta that supplies blood to gonads and genitalia?

A

the ovarian (gonadal) and internal iliac arteries.

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36
Q

What does the ovarian artery correspond to in males?

A

The ovarian artery corresponds to the male testicular artery, in that they are branches directly from the abdominal aorta

37
Q

At what vertebral level doe the ovarian arteries originate?

A

L2

38
Q

As the ovarian artery descends, what does it pass within?

A

As it descends the artery passes within the suspensory ligament to supply the ovaries via the broad ligament.

39
Q

What does the ovarian artery anastomose with?

A

Uterine artery

40
Q

Where do the ovarian veins drain into?

A
  • Left
    • Left renal vein
  • Right
    • IVC
41
Q

Where does the uterine artery cross over the ureter?

A

Approximately 2cm superior to the ischial spine, the ureters run underneath the uterine artery.

42
Q

What is A?

A

Ovarian artery

43
Q

What is B?

A

Ureter

44
Q

What is C?

A

Vaginal artery

45
Q

What is D?

A

Pudendal artery

46
Q

What is E?

A

Uterine artery

47
Q

What is F?

A

Ovary

48
Q

What is commonly damaged during caesarean section or hyperectomy?

A

Due to the close proximity of the ureter and bladder to the female reproductive organs, it is not uncommon that either can be damaged during a caesarean section or hysterectomy (removal of the uterus)

49
Q

What does lymphatic drainage of the internal pelvic organs follow?

A

The lymphatic drainage of the internal pelvic organs largely follows the arterial supply and venous drainage described above.

50
Q

Which group of lymph nodes drains the ovary?

A

Para-aortic lymph nodes

51
Q

What is the lymphatic drainage of the following:

  • fundus and upper uterine body
  • most parts of uterine body
  • uterine cervix and upper vagina
  • lower vagina
A
  • Fundus and upper uterine body
    • Pre-aortic group
  • Most part of uterine body
    • Iliac
  • Uterine cervix and lower vagina
    • Internal iliac and sacral
  • Lower vagina
    • Inguinal and femoral nodes
52
Q

What kind of glands are the breasts?

A

The breasts are highly modified exocrine glands

53
Q

Where do the breasts lie in?

A

Lying in the superficial fascia of the pectoral region

54
Q

How many lobes does each breast consist of?

A

Each breast consists of 15-25 lobes

55
Q

What are the breasts composed of?

A

Each breast consists of 15-25 lobes with tubulo-acinar glands (parenchyma) and stroma (connective tissue).

56
Q

From what ribs does the breasts extend between vertically?

What do the breasts extend between horizontally?

A

Breast extends vertically from the 2nd rib to the 6th or 7th rib and horizontally from the lateral border of sternum to the mid-axillary line.

57
Q

The deep surface of the breast is related to what muscles?

A
  1. Pectoralis Major
  2. Pectoralis Minor
  3. Serratus Anterior
58
Q

What is the axillary tail of the breast?

A

The axillary tail of the breast is an extension of the breast tissue into the axilla, and is important to appreciate in the spread of breast cancer (more on this later)

59
Q

What is the breast also called?

A

Mammary gland

60
Q

Branches of what arteries supplies the breasts?

A

The mammary gland is extremely vascular. They are supplied by branches of subclavian and axillary arteries.

61
Q

What is A?

A

Lateral thoracic artery

62
Q

What is B?

A

Intercostal arteries

63
Q

What is C?

A

Internal thoracic artery

64
Q

What is D?

A

Subclavian artery

65
Q

List the main group of lymph nodes draining the breast tissue and their area of drainage?

A
  1. Parasternal
  2. Supraclavicular
  3. Pectoral (anterior)
  4. Subscapular (posterior)
  5. Abdominal
66
Q

Which group of lymph nodes first receives lymph from the lateral part (quadrant) of the breast tissue?

A

Axillary lymph nodes

67
Q

Why are malignant cells of the breast able to spread so easily?

A

Due to the vascularity and good lymphatic drainage of the breast, malignant cells can quickly spread either to the opposite breast, or to other sites in the body (bone, lung, brain)

68
Q

What are the treatment options for breast cancer?

A

1) Chemotherapy +/- Hormone Treatment (depending on the sub-type of breast cancer)

2) “Lumpectomy” + lymph node Biopsy (removal of suspicious lump, with surrounding biopsy of cancerous ‘hot’ lymph nodes – these are tagged using radioactive dye

3) Mastectomy + Axillary Clearance – Removal of breast + axillary tail.

69
Q

What changes the histology of breast tissue?

A

Breast tissue undergoes cyclical changes in activity, controlled by hormones involved with the ovarian cycle.

70
Q

What is this?

A

Inactive breast

71
Q

What is this?

A

Active breast during (pregnancy or lactation not sure)

72
Q

What is this?

A

Active breast during (either pregnancy or lactation not sure)

73
Q

What changes the histology of the female reproductive system?

A

Study the below slides of female reproductive organs specifically the uterus, ovary and uterine (fallopian) tubes – click on each label to view the online histology, and changes related to hormones excreted from the pituitary gland.

74
Q

What is this?

A

Proliferative phase of uterus

75
Q

What is this?

A

Secretory phase of uterus

76
Q

What is this?

A

Uterine tube

77
Q

What are the layers of the uterine tube?

A
  1. Adventitia
  2. Muscularis mucosa
  3. Mucosa
  4. Lumen
78
Q

NEED TO ADD HISTOLOGY OF TYPES OF FOLLICLE

A
79
Q

NEED TO ADD HISTOLOGY OF OVARY

A
80
Q

What does the placenta develop from?

A

It develops from the trophoblast following implantation of the blastocyst into the uterine endometrium

81
Q

What are the differences between the 2 surfaces of the placenta?

A
  • Maternal side
    • That one surface of the placenta is disc shaped and the structure is rough and spongy
  • Foetal side
    • The reverse side is smooth and bears the attachment of the umbilical cord.
82
Q

Which of A and B is the maternal and foetal side of placenta?

A

A - foetal surface

B - maternal surface

83
Q

What are 4 functions of the placenta?

A
  1. Gaseous exchange
  2. Metabolic transfer
  3. Hormone secretion
  4. Foetal protection
84
Q

At what stage of labour does the placenta physiologically separate from the uterine wall?

A

Third stage of labour

85
Q

What can you see here?

A

Look carefully at the cut-end of the umbilical cord, you should be able to see at least three structures - these are the two umbilical arteries and single umbilical vein.

86
Q

What is the function of umbilical arteries in the foetal circulation?

A

Delivery oxygenated blood with nutrients to foetus

87
Q

What structure (ligament) does the umbilical vein persist as?

A

Ligamentum teres

88
Q

What is the function of umbilical veins in the foetal circulation?

A

Return waste products an CO2 to mother circulation

89
Q

What is structure labelled W?

A

Wharton’s jelly