Repro Tract Infections

Question 1

Best way to test for Trichomonas

Answer 1

NAAT (nucleic acid amplification test)

Question 2

Treatment for Trichomonas

Answer 2

Metronidazole

Question 3

Chlamydia trachomatis morphology

Answer 3

Non-motile, gram negative intracellular pathogen

Question 4

3 ways to transmit Chlamydia

Answer 4

Sexual
Vertical
Fomite

Question 5

Risk of ___ in neonates from Chlamydia infection

Answer 5

Conjunctivitis in neonates that can lead to blindness

Question 6

PID from Chlamydia can lead to what 3 things

Answer 6

Ectopic pregnancy
Infertility
Chronic pelvic pain

Question 7

Best test for Chlamydia

Answer 7

Nucleic Acid Amplification

Question 8

2 antibiotics that can be used for Chlamydia

Answer 8

Doxycycline
Azithromycin
(Erythromycin is second line)

Question 9

Follow up after treatment for Chlamydia

Answer 9

Abstain from unprotected sex until multipledose therapy is complete or 7 days after single dose
Test of cure at 6 months (early if pregnant)
Screen for other STIs
Counsel safe sex practices

Question 10

Neisseria gonorrhea morphology and what cell types do they like to effect

Answer 10

Gram negative diplococcus

Likes columnar, cuboidal and non-keratinized squamous epithelium (the urogenital tract!)

Question 11

2 ways to test for gonorrhea

Answer 11

NAAT

Culture (good to test for antimicrobial sensitivities)

Question 12

Treatment for gonorrhea

Answer 12

Ceftriaxone

Azithromycin can be used as second line, but there is resistance

Question 13

PID

Answer 13

Infection/inflammation of the endometrium, fallopian tubes, pelvic peritoneum, surrounding structures
Cervix is usually a pretty good barrier to upper genital infections

Question 14

6 complications from PID

Answer 14

Tubo-ovarian abscess
Sepsis
Infertility
Ectopic pregnancy
Chronic pelvic pain
Increased risk of recurrent PID

Question 15

Fitz-Hugh-Curtis Syndrome

Answer 15

Inflammation of the liver capsule
Characterized by RUQ pain, nausea, vomiting, and fever
Generally accompanied by evidence of PID of physical exam
An upper tract infection that has gone into the abdomen

Question 16

Signs of PID

Answer 16

Cervical motion tenderness
Adnexal tenderness on bimanual exam
Adnexal mass
Cervicitis
Fever
Vomiting

Question 17

PID Treatment

Answer 17

Cefixime or Ceftriaxone plus azithromycin or doxycycline

Question 18

4 General ways to diagnose pathogens

Answer 18

Antigen based testing
Antibody (from host against infection)
Culture
DNA (NAAT)