Repro Genetics Quiz

Question 1

What gestation is CVS done at?

Answer 1

11-14 weeks

Question 2

What gestation is amniocentesis done at?

Answer 2

> 15 weeks

Question 3

What type of DNA does NIPT test for?

Answer 3

Placental DNA

Question 4

What is the predictive value of NIPT?

Answer 4

90% (not diagnostic)

Question 5

What infections does a TORCH screen look for?

Answer 5

Toxoplasmosis, rubella, cytomegalovirus, herpes simplex and HIV

Question 6

What is the importance of maternal Ro and La

Answer 6

indicates SLE - can cause heart bloc in foetuses

Question 7

Chromosome Microarray detects

Answer 7

imbalance in chromosomes (high resolution)

Question 8

A foetus that is small for dates at 28 week could be caused by…

Answer 8

IUGR, placental dysfunction (PET?)

Question 9

26 week gestation (anencephaly) termination of pregnancy, which drug is used first?

Answer 9

potassium chloride (foetocide)
and then Syntocinon

Question 10

Rhesus -ve pregnant woman has anti-D antibodies and a heterozygous D +ve partner what is the next appropriate test?

Answer 10

NIPD - rhesus type the baby

diagnostic test