Repro-Endo: Male Repro Flashcards
(3) Gonadal Ridge Cell Types
- Mesenchymal cells
- Mesothelial cells
- Primordial cells
Timing of Testosterone?
Internal Structure Differentiation?
External Structure Differentiation?
8th Week
Internal Stimulates Development of the:
vas Deferens
Seminal Vesicles
Epididymis
External Stimulates the Development of the:
None
Timing of Mullerian-inhibiting Factor?
Internal Structure Differentiation?
External Structure Differentiation?
8th Week
Internal Stimulates the Development of the:
Inhibits development of Uterus, Fallopian Tubes, Cervix,
and Upper Vagina
External Stimulates the Development of the:
None
Timing of Dihydrotestosterone?
Internal Structure Differentiation?
External Structure Differentiation?
9th - 12th Weeks
Internal Stimulates the Differentiation of the:
Prostate
External Stimulates the Differentiation of the:
Penis and Scrotom
SRY timing?
7th Week
The sex-determining region (SRY) gene on the
Y Chromosome encodes the
Testis-determining Factor (TDF).
The Mesenchymal cells become the _____ and
then differentiate into the _____.
The Mesenchymal cells become
the Gonadal Ridge Medulla and then
differentiate into the Leydig cells in Males and Ovarian Support Stroma in Females..
The Mesothelial cells differentiate into the _____ and
then into the ______.
The Mesothelial cells differentiate into the Gonadal Ridge and Primary Sex Cord Cortex and
then into the Seminiferous Tubules in Males and
Ovarian Follicles in Females..
The Primordial germ cells differentiate
into the _____ and then into the _____.
The Primordial germ cells differentiate
into the Primary Sex Cords as Future Gametes and
then into the Spermatogonia in Males and
Oogonia in Females .
The Ovaries differentiate into the ____ and the _____.
The Ovaries differentiate into the Theca and the Granulosa.
The Testis differentiate into the ____ and the _____.
The Testis differentiate into the Sertoli cells
and the Leydig cells.
Estrogen from the ____ and ____ help the
Paramesonephric Duct to differentiate into (4) _____.
Estrogen from the Theca and Granulosa help the
Paramesonephric Duct to differentiate into:
- Uterus
- Fallopian tubes
- Cervix
- Upper 1/3 Vagina
Testosterone from the ____ help the
Mesonephric duct to differentiate into (3) _____.
Testosterone from the Leydig cells help the
Mesonephric duct (Wolffian duct) to differentiate into:
- vas Deferens
- Epididymis
- Seminal vesicle
The 4th week, the (5) Mesenchymal swelings covered w/ Ectoderm form around the Cloacal membrane.
The 4th week, the (5) Mesenchymal swelings covered w/ Ectoderm form around the Cloacal membrane.
- Genital tubercle
- Urogenital folds (2x)
- Labioscrotal folds (2x)
What does the Gubernaculum do?
- The Gubernaculum is a ligament
- Forms between the Indifferent gonads and the Labioscrotal swellings
- Guides the Testes into the Scrotum and forms the Round Ligament of the Uterus and Several ligaments of the Ovary.
The Middle of the Primary sex cords differentiate during the? (7th week, SRY)
The Middle of the Primary sex cords differentiate during the? (7th week, SRY)
Coiled, Solid Testis cords
The Ends of the Primary sex cords differentiate during the? (7th week, SRY)
The Ends of the Primary sex cords differentiate during the? (7th week, SRY)
Stay straight, Join near Hilum - Rete testes
The Rete testes and the Mesonepric tubule remnants differentiate into?
(7th week, SRY)
The Rete testes and the Mesonepric tubule remnants differentiate into?
(7th week, SRY)
Efferent ductules
The Mesenchym thickening differentiats into?
(7th week, SRY)
The Mesenchym thickening differentiats into?
(7th week, SRY)
Tunica Albuginea
The Mesothelial cells of the Testes differentiate into the?
(7th week, SRY)
The Mesothelial cells of the Testes differentiate into the?
(7th week, SRY)
Sertoli cells
The Mesothelial cells of the Testes between the Testis cords, differentiate into the?
(7th week, SRY)
The Mesothelial cells of the Testes between the Testis cords, differentiate into the?
(7th week, SRY)
Leydig cells
Fate of the Genital Tubercle (Phallus)?
Fate of the Genital Tubercle (Phallus)?
Genital Tubercle (Phallus) –> Glans (Foreskin or Prepuce)
Fate of the Urogenital Sinus and Urogenital folds?
Fate of the Urogenital Sinus and Urogenital folds?
Urogenital sinus, is made up of the Urogenital folds
Urogenital folds –> Ventral Shaft
The fusion process leaves a line called the
Scrotal/penile raphe
Fate of the Labioscrotal swelling?
Fate of the Labioscrotal swelling?
Labioscrotal swelling –> Scrotom
(8) Derivatives of the Mesonephric duct?
(8) Derivatives of the Mesonephric duct?
- Ureter
- Renal pelvis
- Calyces
- Collecting tubules
- Ductus (vas) defeerens
- Duct of Epididymis
- Ejaculatory duct
- Seminal vesicle
Derivatives of the Paramesonephric duct in Males?
Derivatives of the Paramesonephric duct in Males?
NONE
(4) Derivatives of the Urogenital Sinus?
(4) Derivatives of the Urogenital Sinus?
- Urinary bladder
- Urethra
- Prostate gland
- Bulbourethral glands
Derivatives of the Gubernaculum?
Derivatives of the Gubernaculum?
“Scrotal Ligament”
Genital tubercle –>
Genital tubercle –> Glans penis
Urogenital sinus –>
Urogenital sinus –> Corpus spongiosum
and Bulbourethral glands (of Cowper)
and Ventral shaft of Penis (penile urethra)
Labioscrotal swelling –>
Labioscrotal swelling –> Scrotum
External oblique muscle aponeurosis –> (Spermatic cord)?
External oblique muscle aponeurosis
–> External spermatic fascia
Internal oblique muscle –> (Spermatic cord)?
Internal oblique muscle –> Cremaster muscle
Transversalis fascia –> (Spermatic cord)?
Transversalis fascia –> Internal spermatic fascia
Extraperitoneal fatty tissue –> (Spermatic cord)?
Extraperitoneal fatty tissue –> Areolar tissue
Peritoneum –> (Spermatic cord)?
Peritoneum –> Processus vaginalis
Stages of Spermatogenesis?
Stages of Spermatogenesis?
- Spermatogonium (Diploid, 2N) (1x)
- -> Mitosis –> - Primary Spermatocyte (Diploid, 4N) (1x)
- -> Meiosis I –> - Secondary Spermatocyte (Haploid, 2N) (2x)
- -> Meiosis II –> - Spermatid (Haploid, 2N) (4x)
- -> Phagocytosis –> - Spermatozoan (4x)
The pathway sperm take to exit the body?
The pathway sperm take to exit the body?
SEVEnup
- *S**eminiferous tubules (site of Spermatogenesis)
- *E**pididymis
- *V**as Deferens
- *E**jaculatory Ducts
- *U**rethra
- *P**enis