Repro Clincial Flashcards
bartholin’s cyst
- most common vulvovaginal tumor
- less than 3 cm = asympt
- usually unilat swelling
vaginal trauma
most common cause is sexual assault
cystocele
anterior vaginal prolapse
rectocele
posterior vaginal prolapse
VIN III/Squamous Cell Carcinoma in situ: Usual type
HPV16, smoking, immunocompromised status
VIN III/Squamous Cell Carcinoma in situ: Differentiated VIN
not associated with HPV, more commonly associated with Lichen Sclerosis
Paget’s Dz: vulva
Occurs in postmenopausal white F & can also occur in nipple areas of the breast
- have underlying carcinoma (breast or colon)
- Sx: itching & tenderness
- fiery red background with white plaque like lesions
Squamous Cell Vulvar Carcinoma
Postmenop. females bt 70-80 y/o
- pruritic, raised, ulcerated, pigmented or warty in appearance usually on labia majora
- Spread: direct extension, lymphatic embolization to regional LNs, hematogenous spread to distant sites (Lung, liver, bone)
Verrucous Carcinoma
- Lesions are cauliflower-like
- Radiation is contraindicated –> induce anaplastic transformation
Vaginal Intraepithelial Neoplasia (VAIN)
-HPV virus related
50-90% of pts with VAIN will have coexistent or prior neoplasia or cancer of the cervix or vulva
-Dx: asymptomatic, considered with an abnorm pap
Sarcoma Botryoides
- Presents as a mass of grape-like polyps protruding from the introitus
- tumor is embryonal rhabdomyosarcoma
- 2-3 y/o
- Tx: surgical resection, chemo, +/- radiation
Bacterial Vaginosis
-M.C. cause of vaginitis
-Gardnerella vaginalis
RFs: new/multiple sex partners, smoking, IUD, douching
-Sx: malodourous fishy amine odor especially after intercourse, profuse thin milky discharge often
-Dx: clue cells in saline wet mount, KOH + whiff test, vaginal fluid pH > 4.5
-Tx: Metronidazole BID x 7 days
Meyer-Rokitansky-Kuster-Hauser syndrome
complete lack of development of the paramesonephric system results in Mullerian agenesis = absence of the uterus and most of the vagina
Ovarian Torsion
complete or partial rotation of the ovary on its ligmentous supports, which often results in impedance of it’s blood supply
primary RF: ovarian mass > 5 cm
Adnexal torsion
ovary & fallopian tube both twist