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cns 17f / rep 17m > Repro 2017 M > Flashcards

Repro 2017 M Flashcards

1
Q 
What are the hormone receptors that have genetic variants which are responsible for early menopause estrogen
A. progesterone
B. testosterone
C. FSH
D. GnRH
A

C

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2
Q 
At what stage of life does spermatogenesis start?
A. fetal
B. neonatal
C. childhood
D. puberty
E. adult
A

D

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3
Q 
What does this arrow represent
A. estrogen
B. inhibin
C. progesterone
D. FSH
A

C

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4
Q 
An endometrial biopsy of a 42-year old women revealed complex glands with nuclear atypia and scant intervening stroma. What cancer might she develop later?
A. Leiomyosarcoma
B. Squamous cell carcinoma
C. Adenocarcinoma
D. Serous Carcinoma
A

C

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5
Q 
A 49 year old woman notes increasing size of her right breast over the past year. It is not painful, but the heaviness is causing discomfort. Mammogram shows a 12 cm circumscribed mass. Biopsy is taken, and under microscope, atypical cellular stromal component and benign duct epithelial component are seen. What is most likely the diagnosis?
A. Fibroadenoma
B. Phyllodes tumor
C. Sclerosing adenosis
D. Hamartoma
E. Medullary carcinoma
A

B

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6
Q 
What is a complication of pre-eclampsia?
A. Reduced inflammation
B. Reduced oxidative stress
C. Increased placental perfusion
D. Increased endothelial dysfunction
A

D

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7
Q 
A 65 yr old man with progressing dysuria developed burning pain during urination. Microscopy of urine shows no RBCs, leukocytes, glucose, or bacteria. PSA = 8.
A. neisseria gonorrhea
B. prostatic nodular hyperplasia
C. prostatic adenocarcinoma
D. chronic abacterial prostatitis
E. vesicoureteral reflux
A

B

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8
Q

A 40 year old women presented with severe menorrhagia and colicky dysmenorrhea. A hysterectomy and salpingo- oophrectomy was performed and the diagnosis was ademomyosis. Which of the listed abnormalities present in the resected specimen?
A. endometrial tissue present within the hilum of the ovary
B. endocervical tissue present at the surface of the ovary
C. endometrial tissue present at the broad ligament
D. endometrial tissue present at the wall of the uterus
E. ovarian tissue present at the surface of the uterus

A

D

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9
Q 
Brca 1 and brca 2 interact indirectly through binding with the same protein, which of the following proteins binds both brcas at the same time to facilitate DNA repair?
A. Rad51
B. Palb2 
C. Brip1 
D. Atm
A

B

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10
Q

What is associated with female puberty
A. puberty starts with menses
B. LH initially increases only during sleep
C. testosterone has a role in breast development (not exact wording)
D. Tanner stage 2 pubic hair development is inverse triangle

A

B

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11
Q

Which of the following mechanisms is primarily responsible for determining water in human breast milk? A. Exocytosis
B. Transcytosis
C. Reversed pinocytosis
D. Apical transport

A

A

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12
Q

The mechanism by which finasteride relieve signs & symptoms of benign prostatic hyperplasia? A. reduce testosterone synthesis
B. competitively antagonise androgen receptor
C. decrease LH &FSH synthesis
D. decrease dihydrotestosterone synthesis

A

D

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13
Q 
The retromammary space is located between which of the following structures 
A. skin and areola
B. Pectoralis major and minor
C. breast and deep pectoral fascia
D. suspensory ligament and the skin
A

C

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14
Q 
Which lobe of the prostate is least likely to have glandular tissue? 
A. Posterior
B. Inferolateral
C. Medial
D. Isthmus
A

D

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15
Q 
23 year old female complains of abnormal excessive uterine bleeding at irregular interval, pelvic exam and ultrasound exam revealed firm mass on the anterior wall of the uterus, what clinical term best describes the pattern of her bleeding? 
A. Menometrorrhagia
B. amenorrhea
C. polymenorrhea 
D. dysmenorrhea
A

A

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16
Q 
A 6 year old girl presented with vaginal bleeding. On examination, she had well developed breasts and had pubic and axillary hair. Ultrasound showed a solid ovarian mass 6x6 cm. Which of the following would be elevated in the patient
A. Hcg
B. FSH
C. estradiol
D. Progesterone 
E. Inhibin
A

C

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17
Q 
What does the bed nucleus of stria terminalis most likely represent in a male to female transsexual? 
A. heterosexual male
B. heterosexual female
C. homosexual male
D. CAH
A

B

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18
Q 
During pregnancy, what’s the primary site of estriol production? 
A. fetal adrenal cortex
B. placenta
C. maternal ovaries
D. fetal liver
A

B

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19
Q 
A primigravida lady with vaginal bleeding and mild lower abdominal pain. Her last menstrual period was 4 months ago. What’s her gestational age in weeks?
A. 16 w
B. 17w 
C. 18w 
D. 19w
A

B

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20
Q

According to naeglele’s, which of this will have a significant error when you calculate the expected day of delivery?
A. Uterine cycle of 35 days
B. Frequency of 10 days
C. Using hijri date

A

(not sure about answer 😅)?

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21
Q

Why the placenta is unable to convert DHEA to estradiol?
A. placenta lacks reactive components
B. placenta lacks cyp19
D. fetal-placental-maternal transport of DHEA

A

( not sure about answer 😅 )

22
Q 
What is a semi-objective way to assess menstrual bleeding? 
A. Pad pictogram
B. number of vulva pads
C. clots
D. day of menstruation
A

A

23
Q 
A 30-year old woman presented at 30 weeks gestation for routine check up. Pregnancy tests are eventful so far. An ultrasound was performed last week. The report indicates that the fetal growth matches gestational age and that amniotic fluid level is normal. What do you expect the symphysis-fundal height (in centimetres) ?
A. 28+- 1
B. 30+-1
C. 30+-2
D. 32+-1
E. 32+-2
A

C

24
Q

What are the major hormones is postmenopausal women
A. estrone and LH
B. estrone and FSH
C. estradiol and and LH

A

B

25
Q

Which of the following is not an action of sertoli cells?
A. stimulate differentiation of leydig cells
B. produce mullerian regression factor
C. produce dihydrotestosterone

A

C

26
Q

Which one of the following statements applies to Nandronolone?
A. causes virilizaition more than testosterone in females (paraphrasing)
B. can delay the epiphysis closure in children
C. Is useful in patients with hypoproteinemia
D. Enhances the pituitary LH secretions (paraphrasing)

A

-

27
Q 
What structure develops in a male fetus from the proximal mesnephric tubules 
A. vas deferense
B. efferent ductules of the testis
C. epididymus
D. seminal vesicle
A

B

28
Q

What is the best modality for diagnosing abdominal undescended testis?
A. MRI
B. Ultrasound

A

A

29
Q

What is the effect of mutation in MTHFR?
A. cleft lip and palate
B. kidney agenesis
C. focal phocomelia

A

A

30
Q

Which one of the following is due to Valproate?

A

Cleft lip

31
Q

What drug is used with tamoxifen?

A

letrozole

32
Q 
What is true about Alprostidil ?
A. It was originally developed as blood pressure lowering medication 
B. it stimulates the production of cGMP
C. it stimulates the production of cAMP
D. it is an inhibitor of PDE5
A

C

33
Q 
Which of these tumors is radiosensitive 
A. granulosa cell tumor
B. yolk sac tumor
C. dysgerminoma
D. choriocarcinoma 
E. encysted teratoma
A

D

34
Q 
During hysterectomy and oophorectomy, the uterine and ovarian vessels must be ligated. These vessels can be found in which ligaments?
A. Round and Ovarian
B. Broad and Suspensory
C. Broad and Ovarian
D. Round and Suspensory 3
A

B

35
Q 
A pregnant lady presenets to the clinic with a history of osteomalacia in previous pregnancy. After examination the doctor told her she will need to do to a C-section. What type of pelvis does she have?
A. Platypelloid
B. Gynecoid
C. Android
D. Anthropoid
A

A

36
Q 
30 y/o women presented with distended abdomen and lower abdominal pain on examination she had 12 (mm or cm) mass on the right ovary , on biopsy it was composed of 3 germ layers (ectoderm, mesoderm, endoderm) , what’s the diagnosis?
A. squamous cell carcinoma
B. adenocarcinoma 
C. sarcoma
D. Thyroid tumor
E. Mature teratoma
A

E

37
Q 
30yr old primigravida presents early in labour at 42 weeks gestation. She is obese(BMI=32kg/m2) and says she gained 20 kg during pregnancy. She was diagnosed with gestational diabetes during her 7th month of pregnancy but was not compliant with dietary instructions and did not attend clinic for the past 2 months. What do you expect the baby's birth weight to be?
A- 1500-2000
B- 2000-2500 
C- 2500-3000 
D- 3000-4000 
E- 4000-4500
A

E

38
Q

What artery supply the medial side of breast ?

A

Internal thoracic artery

39
Q

Mother comes to clinic a few weeks after birth because of painful nipples. she was referee to a neonatologist. what is the underlying cause?
A. Oral candidiasis
B. Torticollis
C. Short frenulum Cleft lip

A

(not sure about the answer)

40
Q

What is a property of a category c drug ?
A. Experimental studies show adverse effect of drug B. Drug has no known fetal risk
C. Drugs potential risks outweigh drug benefits

A

A

41
Q 
What is the average pelvic cavity diameter in adult female? 
A. 9
B. 10
C. 11
D. 12 
E. 13
A

D

42
Q 
Which maternal condition should be treated so it doesn’t result in congenital anomalies? 
A. essential HTN
B. PKU
C. renal failure
D. bronchial asthma
A

B

43
Q 
When does oogenesis starts in female? 
A. Fetal period
B. Neonatal period
C. Childhood
D. Puberty 
E. Adulthood
A

A

44
Q 
When does spermatogenesis starts in males 
A. Fetal period
B. Neonatal period
C. Childhood
D. Puberty 
E. Adulthood
A

D

45
Q

A 20-year old women recently married is experiencing severe pain in her lower abdomen & pelvis during intercoarse, what is she suffering from?
A. Deep dyspareunia
B. Superficial dyspareunia

A

A ( not sure )

46
Q 
A 65 year old woman presented with vaginal bleeding, she is a mother of 5 children & healthy. Pevic US shows normal ovaries & uterus with thin endometrial lining. Pap smear & biopsy are normal what is the histopathological finding?
A. Adenocarcinoma
B. Chronic inflammation Hyperplasia
C. Atrophy
D. Squamous cell carcinoma
A

C

47
Q

A 52 yr old women with bone density -2.2 on t-score, what does that indicate?
A. Osteoporosis
B. osteopenia
C. Oseteocarcinoma

A

B

48
Q 
A 40 years old woman with endometriosis underwent pelvic ultrasound scan. The report indicated a retroverted retroflexed uterus . In this retroversion, the uterus is tilted towards which organ?
A. Right ovary
B. Left ovary
C. Bladder 
D. Urethra 
E. Rectum
A

E

49
Q

What is the characteristic of granulosa lutein cells?
A. Secrete progesterone
B. Small and dark staining
C. Abundant RER
D. Derived from theca interna
E. Makes up small amount of corpus luteum

A

A

50
Q 
A 32 yr old male noticed increasing heaviness in the scrotoum for the past 10 years. On physical examination, his left testis was 3 times the size of the right testes and was hard on palpation. An ultrasound revealed a 6 cm solid mass in the body of the left testes. Laboratory examination revealed increase in alpha fetal protein. What is the most likely diagnosis of this testicular mass?
A. Teratoma
B. Yolk sac tumor 
C. Choriocarcinoma 
D. Seminoma
E. Leydig cell tumor
A

B

51
Q

Why does the fetus use DHEA instead of cortisol?

A

-

cns 17f / rep 17m (2 decks)

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