CNS 2017 F

Question 1

1. During otoscopic examination, the bright cone is normally seen in which quadrant of the tympanic membrane ?
   A. anteroinferior
   B. anterosuperior
   C. posterosuperior
   D. posteroinferior

Answer 1

A

Question 2

What happens in a lesion to both posterolateral parietal lobe?

Answer 2

We don’t know

Question 3

A 75yr old man had a large ischemic stroke in the frontal lobe 15 years ago
What will you find when you see the brain grossly now? (Not the exact wording but same idea)
A. Cystic cavities
B. Edema
C. Petechial hemorrhage
D. Rupture of aneurysm of circle of willis

Answer 3

A

Question 4

A vaccine against which microorganism is required as prophylaxis to those in close contacts with infected patients?
A. Haemophilus influenzae B. Strept pneumo
C. Listeria

Answer 4

A

Question 5

Which drug increases prolactin and lowers testosterone?

Answer 5

Rametleon

Question 6

Lesion in the temporal lobe causes what visual defect?
A. homonymous hemianopia B. pie in the sky

Answer 6

B

Question 7

A man was stabbed on the left side of his face & the parotid gland along with hypoglossal nerve were damaged, what will we see in this patient?
A. loss of sensation on the left side
B. loss of temp on the left side
C. loss of proprioception on the left side
D. the tongue is directed to the left side when the patient protrudes it

Answer 7

D

Question 8

Loss of sensation in the left upper limb & left jaw

Answer 8

Right middle cerebral artery damage

Question 9

A repeated question about MS worsening with increased temp (Uthoff’s phenomenon – from PBL)

Answer 9

-

Question 10

Which thalamus nuclei are responsible for emotional instability & spontaneous laughing or crying?

Answer 10

dorsomedial nuclei

(the other options were other thalamic nuclei)

Question 11

What will happen when this area is damaged?
A. The patient can see but can’t reach an object
B. The patient can draw the object but can’t identify it
C. The patient can identify the object but can’t draw it

Answer 11

B

Question 12

Imipramine MOA (mode of action)

Answer 12

Know that it is a tricyclic antidepressant and that it inhibits serotonin & NA uptake, and blocks potassium, histamine, and muscarinic receptors.

Question 13

A question about a female patient who presented with a history of intermittent vision loss as well as muscle weakness and trouble in coordination (MS symptoms in general).

Answer 13

optic neuritis

Question 14

Which drug is an inducer of an enzyme leading to many drug-drug interactions?
A. Phenytoin
B. ethosuximide
C. Vigabatrin
D. Cannabinoids

Answer 14

A (also carbamazepine is a correct answer if it was written instead of phenytoin)

Question 15

There was a question about the definition of prodrugs.

Answer 15

the answer was along the lines of “a drug that gets into its active form after being metabolized”

Question 16

What is the mechanism by which tramadol works?
A. M receptor agonist and serotonin norepinephrine reuptake inhibitor
B. GABA
C. Increase intracellular calcium

Answer 16

A

Question 17

From which nucleus does the spinal tract of the trigeminal originate?
A. Ipsilateral spinal trigeminal nucleus
B. Contralateral spinal trigeminal nucleus
C. Sensory trigeminal nucleus

Answer 17

we are not sure tbh

Question 18

What part of the auditory pathway is affected if there is an occlusion to the posterior cerebral artery?

Answer 18

we don’t know the answer

Question 19

What structures form lentiform nucleus
A. Caudate nucleus and globus pallidus
B. Caudate nucleus and substantia nigra
C. Caudate nucleus and putamen
D. Putamen and globus pallidus

Answer 19

D

Question 20

What cortex is the most affected with age?
A. Prefrontal cortex
B. Cerebellar cortex

Answer 20

A

Question 21

What drug causes purple mottling of skin?

Answer 21

Amantadine

Question 22

What drug causes insomnia if administered after mid afternoon?

Answer 22

Selegiline

Question 23

What is the first enzyme that is responsible for the initiation of Alzheimer disease ?
A. Alpha secretase
B. Beta secretase
C. Gamma secretase
D. Delta secretase

Answer 23

B

Question 24

Why is xanthine oxidase considered an insignificant source of superoxide anion in eschemia-reperfusion in the brain
A- low levels of ATP concentration
B- inhibition of xanthine oxidase
C- increased ATP concentration
D- increased NADPH concentration

Answer 24

A

Question 25

PSNS nucleus of facial nerve?

Answer 25

Superior salivatory nucleus

Question 26

In the CSF, what is the standard test to detect viruses for aseptic meningitis/encephalitis?
A) Viral culture
B) PCR
C) Direct antigen detection
D) ELISA

Answer 26

B

Question 27

Which of the following is the type of N. meningitidis vaccine? A) Conjugate
B) Live attenuated
C) Recombinant
D) Killed
E) Subunit

Answer 27

A

Question 28

How does the ear locate the source of the sound vertically? (this was the concept of the question)
A- locate the level difference
B- time difference
C- spectral analysis

Answer 28

C

Question 29

Which tract decussates at the level of superior colliculus in the midbrain?
A. Corticospinal
B. Rubrospinal
C. Medial lemniscus
D. Lateral lemniscus

Answer 29

B

Question 30

Which of the following is involved in defective pathway of Hereditary spastic paraplegia ?
A. Anterograde Retrograde transporter
B. Defective WNT signalling pathway.
C. Endosomal trafficking

Answer 30

A

Question 31

Ptosis is caused by a lesion of which nerve?
A. Optic
B. Oculomotor
C. Trochlear
D. Trigeminal
E. Abducent

Answer 31

B

Question 32

A patient presented with acute meningitis and the causative organism was a gram positive bacilli. What antibiotic treatment is best?
A. Gentamicin + tetracycline B. Vancomycin + something C. Ciptriaxone + something D. Ampicillin + gentamicin

Answer 32

D

Question 33

Which of the following plays a key role in the formation of on & off receptive fields? A. retinal ganglion cells
B. bipolar cells
C. lateral amacrine cells
D. rods & cons

Answer 33

B or C (we don’t know)

Question 34

What CNS tumors show verocay bodies?

Answer 34

Shwannomas

Question 35

“A question about microvascular proliferation or necrosis (glioblastoma [Grade IV])”

Answer 35

-

Question 36

We don’t remember the exact scenario but it was asking about the finding in this image (there might’ve been extra signs and symptoms in the question).

Answer 36

The affected vessel is the middle cerebral artery.