Replicative cycles Flashcards
What are the two key variables used to classify viruses that infect animals
- an RNA or DNA genome, either single stranded or double stranded
- the presence or absence of a membranous envelope
(whereas few bacteriophages have an envelope OR an RNA genome, many animal viruses have both
Viral envelopes
- many viruses that infect animals have a membranous envelope
-viral glycoproteins on the envelope bind to specific receptor molecules on the surface of a host cell
-the viral envelope is usually derived from the host cell’s plasma membrane as the viral capsids exit - other viral membranes form from the host’s nuclear envelope and are then replaced by an envelope made from golgi apparatus membrane (i.e herpesvirus)
Retrovirus
use reverse transcriptase to copy their RNA
provirus
viral DNA that is integrated into the host genome is called a provirus
vaccine
harmless derivative of a pathogen that stimulates the immune system to mount defenses against the harmful pathogen
3 causes of rapidly emerging viral diseases in humans is mutation
mutation of existing viruses into new ones that can spread more easily
spread of a viral disease from a small isolated human population
spread of existing viruses from other animals
prions
infectious proteins that appear to cause degenerative brain diseases in animals