Replication of DNA Flashcards
The DNA in the chromosomes carries our two functions:
- It reproduces itself. This process is called REPLICATION.
- Supplies the information necessary to make all the RNA and proteins in the body, including enzymes.
The area where DNA replication takes place. ORIGIN OF REPLICATION.
Replication Fork
It is a strand where it replicates CONTINUOUSLY.
Leading Strand
A strand where it replicates DISCONTINOUSLY forming short fragments.
Lagging Strand
Additional Info:
The sequence of DNA that is copied during the synthesis of mRNA.
Template Strand
Additional Info:
Are the short lengths of DNA that are produced by the discontinuous replication of the lagging strand.
Okazaki Fragments
Distinct STEPS in the Replication of DNA.
- Opening up of the superstructure of the chromosomes.
- Relaxation of Higher-Order Structures of DNA.
- Replication of DNA molecules starts with the unwinding of the double helix.
- Primers/Primases
- DNA Polymerase
- Ligation
This reaction eliminates some of the positive charges on histones and weakens the strength of the DNA-histone interaction.
Acetylation-deacetylation
Also called Gyrases
Tropoisomerases
Causes the separation of the double helix.
Helicases
The Okazaki fragments and any nicks remaining are eventually joined by _________.
DNA Ligase
Synthesizes short olingonucleotides (primers)
Primase
Allows the leading strand to be threaded through.
Clamp Protein
Joins the assembled nucleotides.
DNA Polymerase