Replication of DNA Flashcards

1
Q

The DNA in the chromosomes carries our two functions:

A
  1. It reproduces itself. This process is called REPLICATION.
  2. Supplies the information necessary to make all the RNA and proteins in the body, including enzymes.
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2
Q

The area where DNA replication takes place. ORIGIN OF REPLICATION.

A

Replication Fork

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3
Q

It is a strand where it replicates CONTINUOUSLY.

A

Leading Strand

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4
Q

A strand where it replicates DISCONTINOUSLY forming short fragments.

A

Lagging Strand

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5
Q

Additional Info:

The sequence of DNA that is copied during the synthesis of mRNA.

A

Template Strand

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6
Q

Additional Info:

Are the short lengths of DNA that are produced by the discontinuous replication of the lagging strand.

A

Okazaki Fragments

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7
Q

Distinct STEPS in the Replication of DNA.

A
  1. Opening up of the superstructure of the chromosomes.
  2. Relaxation of Higher-Order Structures of DNA.
  3. Replication of DNA molecules starts with the unwinding of the double helix.
  4. Primers/Primases
  5. DNA Polymerase
  6. Ligation
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8
Q

This reaction eliminates some of the positive charges on histones and weakens the strength of the DNA-histone interaction.

A

Acetylation-deacetylation

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9
Q

Also called Gyrases

A

Tropoisomerases

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10
Q

Causes the separation of the double helix.

A

Helicases

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11
Q

The Okazaki fragments and any nicks remaining are eventually joined by _________.

A

DNA Ligase

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12
Q

Synthesizes short olingonucleotides (primers)

A

Primase

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13
Q

Allows the leading strand to be threaded through.

A

Clamp Protein

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14
Q

Joins the assembled nucleotides.

A

DNA Polymerase

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