Replication Flashcards
0
Q
Topoisomerase
A
Relieves supercoiling
1
Q
Helicase
A
Unwinds the DNA
2
Q
DNAa
A
Melts origin of replication
3
Q
SSBs
A
Hold DNA apart
4
Q
DNA pol I
A
Removes RNA primer, replaces with DNA, proof reads
5
Q
DNA pol III
A
Majority of DNA synthesis, extends leading and lagging strands, proof reads
6
Q
DNA ligase
A
Seals the nick
7
Q
Primase
A
RNA pol, makes RNA primer for DNA pol
8
Q
Two words that describe replication:
A
Bidirectional and semiconservative
9
Q
What defect is responsible for Lynch syndrome?
A
defect in mismatch repair; Seen as nonpolyposis colorectal cancer
