Repair, Rgeneration, Fibrosis Flashcards
Most common collagen type in CT
Collagen type I
Temporary extracellular matter of plasma like matrix proteins that accumulate at injury site
Provisional matrix
Migration of cells according to the gradient of adhesive matrix substrates
Haptotaxis
Migration of cells directed by soluble ligands
Chemotaxis
Dried thrombus forming a barrier on wounded skin surface to avoid invasion of microorganisms
Scab or eschar
Disease caused by mutation in epidermal laminin
Epidermolysis bullosa
Immature cells that may differentiate into nearly all cell types
Pluripotent cells
Long linear polymers of specific repeating disaccharides
Glycosaminoglycans
Long, linear polymers of specific repeating disaccharides
Proteoglycans
Non stem cell that has little or no capacity for self renewal
Progenitor cell
Extracellular matrix protein that confers deformability to tissue
Collagen
Excess collagen deposition within tissue
Scarring or fibrosis
Principal proteinases involved in tissue remodeling
Matrix metalloproteinases
Differentiation of a stem cell from on cell type to form cells of another tissue type
Transdifferentiation
Cells that undergo self renewal and have capacity to differentiate into multiple mature lineages
Stem cell
Complicated wound with healing defect developing in an area devoid of sensation because of persistent trauma
Neuropathic ulcer
Principal matrix binding glycoproteins of stromal CT
Fibronectin
Type of wound healing with large tissue damage area not to be completely corrected
Secondary healing
Predominant type of collagen with basement membrane
Collagen type IV
Splitting open of a wound
Dehiscence
Protein cores O-linked to glycosaminoglycan chains
Proteoglycans
