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Pathology > Repair, Rgeneration, Fibrosis > Flashcards

Repair, Rgeneration, Fibrosis Flashcards

1
Q

Most common collagen type in CT

A

Collagen type I

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2
Q

Temporary extracellular matter of plasma like matrix proteins that accumulate at injury site

A

Provisional matrix

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3
Q

Migration of cells according to the gradient of adhesive matrix substrates

A

Haptotaxis

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4
Q

Migration of cells directed by soluble ligands

A

Chemotaxis

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5
Q

Dried thrombus forming a barrier on wounded skin surface to avoid invasion of microorganisms

A

Scab or eschar

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6
Q

Disease caused by mutation in epidermal laminin

A

Epidermolysis bullosa

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7
Q

Immature cells that may differentiate into nearly all cell types

A

Pluripotent cells

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8
Q

Long linear polymers of specific repeating disaccharides

A

Glycosaminoglycans

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9
Q

Long, linear polymers of specific repeating disaccharides

A

Proteoglycans

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10
Q

Non stem cell that has little or no capacity for self renewal

A

Progenitor cell

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11
Q

Extracellular matrix protein that confers deformability to tissue

A

Collagen

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12
Q

Excess collagen deposition within tissue

A

Scarring or fibrosis

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13
Q

Principal proteinases involved in tissue remodeling

A

Matrix metalloproteinases

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14
Q

Differentiation of a stem cell from on cell type to form cells of another tissue type

A

Transdifferentiation

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15
Q

Cells that undergo self renewal and have capacity to differentiate into multiple mature lineages

A

Stem cell

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16
Q

Complicated wound with healing defect developing in an area devoid of sensation because of persistent trauma

A

Neuropathic ulcer

17
Q

Principal matrix binding glycoproteins of stromal CT

A

Fibronectin

18
Q

Type of wound healing with large tissue damage area not to be completely corrected

A

Secondary healing

19
Q

Predominant type of collagen with basement membrane

A

Collagen type IV

20
Q

Splitting open of a wound

A

Dehiscence

21
Q

Protein cores O-linked to glycosaminoglycan chains

A

Proteoglycans

Pathology (7 decks)

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