Cell Injury

Question 1

Macroscopic deposition of calcium salts in injured tissues

Answer 1

Dystrophic calcification

Question 2

Accumulation of cholesterol and cholesteryl esters in macrophages with arterial intima?

Answer 2

Atherosclerosis

Question 3

Brown- black pigment found principally on epidermal cells of the skin

Answer 3

Melanin

Question 4

Type of necrosis where the outline of the cell is maintained

Answer 4

Coagulative

Question 5

Extrusion from the cell of a pkynotic nucleus

Answer 5

Karyolysis

Question 6

The nucleus become smaller and stains deeply basophilic

Answer 6

Pkynosis

Question 7

Removal of hydrogen atom from unsaturated fatty acids of membrane phospholipids

Answer 7

Lipid peroxidase

Question 8

Enzyme responsible for conversion of hydrogen peroxide to hypochlorous acid

Answer 8

Myeloperoxidase

Question 9

Mixture of lipids and proteins containing a golden brown pigment

Answer 9

Lipofuscin

Question 10

Cavity filled with polymorphonuclear leukocyte

Answer 10

Abscess

Question 11

Reversible increase in cell volume

Answer 11

Hydrophobic swelling

Question 12

Principal cause of metastatic calcification

Answer 12

Deranged calcium metabolism

Question 13

Proapoptotic molecule released by mitochondria

Answer 13

Cytochrome c

Question 14

Cellular source of hypochlorous acid

Answer 14

Macrophages and neutrophils

Question 15

Common analgesic that is highly toxic to the liver upon overdose

Answer 15

Acetaminophen

Question 16

What enzyme doesn’t detoxify radical oxygen species

Answer 16

Telomerase

Question 17

Molecule that preserves the viability of injured cells yet propels them towards apoptosis

Answer 17

P53

Question 18

Type of myocardial necrosis

Answer 18

Coagulative necrosis

Question 19

Storage of carbon particles in the lung and regional ln

Answer 19

Anthracosis

Question 20

Type of necrosis caused by insudation of plasma proteins into the wall of injured blood vessels

Answer 20

Fibrinoid necrosis

Question 21

Molecular component of alcoholic hyalin

Answer 21

Cytoskeletal filaments

Question 22

Which of the following doesn’t cause hyperplasia?

Answer 22

Ischemia

Question 23

Type of cell injury usually resulting from obstruction to the flow of blood

Answer 23

Ischemic cell injury

Question 24

Cellular adaptation to diminishes need for more resources for cell’s activity

Answer 24

Atrophy

Question 25

Which is not intracellular target of hydroxyl radical

Answer 25

Lysosomes

Question 26

Process by which an exogenous insult kills the cell

Answer 26

Dysplasia

Question 27

Type of necrosis characteristic of tuberculosis

Answer 27

Caseous necrosis

Question 28

Organelle that stores catalase

Answer 28

Peroxisome