Repair and Regeneration

Question 1

What is healing by Regeneration?

Answer 1

This is restitution with no or minimal residual defect

Question 2

What is healing by Repair?

Answer 2

Loss of some tissue - Fibrosis occurs and scar tissue formed

Question 3

What are the classification of cell times, in terms of multiplying?

Answer 3

Labile
Stable
Permanent

Question 4

What are Labile cell populations?

Answer 4

Multiply continually throughout life

• GI Tract
• Bone Marrow

Question 5

What are Stable cell populations?

Answer 5

Only Multiply when stimulated to.

• Haptocytes
• Endothelium

Question 6

What are Permanent cell populations?

Answer 6

Cannot multiply

• Neurones
• Skeletal Muscle

Question 7

In what cell populations can healing by regeneration occur?

Answer 7

Labile Populations

Stable populations

Question 8

When does Healing by repair occur?

Answer 8

Loss of Parenchymal (ground tissue)

Loss of stromal framework

Question 9

What aare Parenchymal cells replaced with in healing by repair

Answer 9

Granulation tissue

Question 10

What does Granulation tissue consist of?

Answer 10

Fibroblasts
Dense Collagen
Blood Vessels

Question 11

What are the phases of bone repair?

Answer 11

1. Early Fracture - Haemorrhage within bone. Rupture of vessel
2. Inflammatory phase - Removal of Necotic tissue, angiogenesis and fibroblasts and oestoblasts lay down bone
3. Formation of a Callu
4. Remodelling phase