Reoviruses

Question 1

Examples of reovirus

Answer 1

Colorado tick fever (Mountain fever, American Mountain fever) (under genu: Coltivirus)

Question 2

Reoviridae structure

Answer 2

Naked, inner capside is icosahedral, 12 DS RNA segments (positive RNA)

Question 3

Replication style

Answer 3

positive RNA (infectious)

Question 4

Colorado tick fever

Answer 4

fever
males 15-45 years present in summer (April-August)
Tick Bite
Saddleback fever
Headache, myalgias, arthralgias, fatigue
5-15% transient rash
Encephalitis in 3-15 percent of infected children under 10, pericarditis also possible
0.2 percent fatality, 2 week recovery

Question 5

Pathogenesis

Answer 5

Bone marrow cells (arrest development of polymorphonuclear leukocytes, eosinophils, basophils…may cause thrombocytopenia and platelets)
4-5 days after tick bite
Antibody appears after 2 weeks

Question 6

Epidemiology

Answer 6

Wood ticks, small mammal reservoir
Ticks are infected for life once infected. The ticks cannot spread it to each other, they can only get it from rodents.
4,000-10,000 ft elevation
Colorado and Idaho

Question 7

Control

Answer 7

Remove tick immediately, check for ticks, Protect exposed areas from ticks

Question 8

The most common arborviruses

Answer 8

West Nile Virus is the most common, followed by Colorado Tick Fever

Question 9

Colorado Tick Fever has similar symptoms to ____.

Answer 9

Rocky Mountain Spotted Fever