reoviridae

Question 1

reoviridae

Answer 1

REO-> respiratory enteric orphan

Question 2

reoviridae general

Answer 2

nonenveloped, spherical, ds RNA segments 10-12 depending on genus, replication in cytoplasm
segments allow for genetic reassortment

Question 3

subfamilies of reoviridae

Answer 3

sedoreovirinae and spinareovirinae

Question 4

sedoreovirinae important genera

Answer 4

orbivirus-african horse sickness, blue tongue virus

rotavirus-RVA

Question 5

spinareovirinae important genera

Answer 5

orthoreovirus-avian reovirus

coltivirus-colorodo tick fever virus

Question 6

blue tongue

Answer 6

most susceptible host-sheep, fine wool in europe and white-tailed deer. Inapparent infection in cattle which are primary reservoir and amplifying host

Question 7

Blue tongue (BTV)

Answer 7

List A disease, part of orbivirus

10 segments dsRNA genome

Question 8

BTV transmission

Answer 8

transmitted biologically by certain species of culicoides sonorensis
can be venereal or trans placental transmission

Question 9

BTV path

Answer 9

vascular endothelium damage, intravascular coagulation, necrosis of tissues and organs, edema, hemorrhage, congestion, abortion, CNS malformations

Question 10

BTV clinical findings

Answer 10

profuse salivation, edema of muzzle, reddening of nasal mucosae, mucopurulent nasal discharge, often blood stained, crust formation on nostrils and lips
cyanosis on the tongue, necrotic ulceration, erosion of dental pad, necrosis, hyperemia, ulceration in oral cavity, coronitis and laminitis

Question 11

Dx of BTV

Answer 11

immunohistochemical tests such as immunoflourescence and immunoperoxidase test, PCR, ELISA

Question 12

african horse sickness (AHS)

Answer 12

infectious, noncontagious, arthropod bourne disease of horses, donkeys and mules, sometimes dogs List A disease enzootic to sub saharan africa

Question 13

AHS etiology

Answer 13

orbivirus, nine serotypes based on capsid protein VP2 and VP5 variation

Question 14

AHS transmission

Answer 14

cullicoides regularly in most countries of subsaharan africa

Question 15

AHS clinical findings

Answer 15

profuse nasal discharge od serous and froth that may be blood stained, pulmonary edema, interlobular edema of lungs, hydroperitoneum, hydropericardium, edema of muscles, edema of eyelids

Question 16

AHS prevention and control

Answer 16

vaccination in enzootic areas, control of vector, reduced exposure to biting insects, slaughter of sick or viremic

Question 17

rotavirus

Answer 17

major cause of sever viral diarrhea in young animals and birds, 11 segments of dsRNA, VP6 protein variations, RVAs cause the diarrhea

Question 18

RVA strain Wa: G1P1A(8)

Answer 18

G1= is G genotype/serotype
P1A(8): 1 A is P serotype
(8) is Pgenotype

Question 19

rotavirus transmission in animals and humans

Answer 19

infected stool has large number of visions, fecal oral transmission, virus replicates in mature enterocytes on the villi of upper small intestine

Question 20

rotavirus pathogenesis

Answer 20

after ingestion can either infect intestinal villus cells damaged during virus replication and release or NSP4 acts as an enterotoxin

Question 21

rotavirus symptoms

Answer 21

severe diarrhea in young of different animals, profuse diarrhea, anorexia, dehydration and occasionally mild fever, feces are watery to pasty pale yellow sometimes filled with mucous and blood flecks

Question 22

rotavirus Dx

Answer 22

PAGE gel

Question 23

avian reovirus

Answer 23

viral arthritis/tenosynovitis

broilers, turkeys, transmission fecal oral, arthritis common in the hock joint

Question 24

avian reovirus clinical findings

Answer 24

lameness, tensosynovitis, swollen and inflamed hock joints, clear synovial fluid and inflammation of synovial membranes, ruptured gastrocnemius tendons

Question 25

avian arthritic prevention

Answer 25

live and killed vaccines available, passive immunity to chicks