Renin-Angiotensin-Aldosterone system ( RAAS )

Question 1

RAAS is a Hormonal system that controls?

Answer 1

Blood pressure

Question 2

Baroreflex is a what?

Answer 2

Short term response to sudden changes in blood pressure

Question 3

RAAS is what?

Answer 3

Long term regulation

Question 4

In the kidneys, within the walls of afferent aterioles, there are specialized cells producing pro renin called?

Answer 4

Juxtaglomeurlar cells

Question 5

Juxtaglomerular cells are produced upon what?

Answer 5

The drop in blood pressure

Question 6

What the drop in blood pressure tells the juxtaglomerular cells to produce prorenin, what is being produced??
Which then will be released where?

Answer 6

Renin
Into the blood

Question 7

Renin converses plasma proteins called ____
And produced by the ____
Into what? (3)

Answer 7

Angiotensinogen
Liver
Into angiotensin 1

Question 8

Angiotensin 1 ( 10 amino acid peptide )
Which is then converted into what?

Answer 8

Angiotensin 2
( 8 amino acid peptides )

Question 9

Angiotensin II helps with what? (6)

Answer 9

Systemic vasoconstriction
Promotes sodium/water retention
Induces release aldosterone
Stimulate thirst ( hypothalamus )
ADH release ( pituitary )
Reduce baroreflex to increase blood pressure ( hypothalamus )

Question 10

Angiotension 2 is only for how long?
Then what happens?
Which have?

Answer 10

1-2mins
Degraded into angiotensin 3-4
Lesser effects

Question 11

Overactive or inappropriate activated RAAS is caused by?

Answer 11

Hypertension

Question 12

ACE inhibitors & Angiotensin receptors blockers are common treatment for ?

Explain Why?

Answer 12

Hypertension

Because the whole point of RAAS is to help increase blood volume & pressure
But since hypertension is high BP, giving these medications help stop the RAAS from already increase more BP