Renal Tubule reabsorption and secretion Flashcards
1
Q
What molecules are reabsorbed in the proximal convoluted tubule?
A
- glucose
- sodium
- water
- amino acids
2
Q
What is reabsorbed in the Descending Limb of the Loop of Henle?
A
- Water
3
Q
What is absorbed in the Thick Ascending Limb of the Loop of Henle?
A
- Reabsorbs ions
- Na, Ca, Mg, K, Cl
4
Q
What is absorbed in the Distal Convoluted Tubule?
A
- Ions
5
Q
What is absorbed in the Collecting Duct?
A
- reabsorbs water and ions if necessary
6
Q
Main types of transporters in the tubule
A
- channels (aquaporins, sodium channels)
- transporters (glucose transporter, sodium/glucose symporter, antiporters - sodium/hydrogen exchanger)
- primary active transporter (sodium/potassium ATPase)
7
Q
What is diabetes mellitus?
A
- high concentration of glucose in urine due to high concentration of glucose in plasma
- tubule cannot absorb all the glucose
- high concentration of glucose in urine = high volume of urine due to osmosis
8
Q
True/False - Most drugs that are filtered into Bowman’s capsule due to not being bound to proteins are reabsorbed in the tubule system
A
False - most drugs that enter the tubule system are not reabsorbed
9
Q
What part of the tubule has many drug transporters which allows for selective secretion of drugs from the blood?
A
The proximal tubule
