Renal Transplant Flashcards
How much time on average does renal transplant add to patients live compared to dialysis
on average 10 years
What is matched between patient and donor in kidney transplant
HLA type A,B,C on chromosome 6
They dont have to fully match by - weaker matches are more likely to get rejected
Treatment is given to disensitise them to donor HLA when there is a living donor
Typical scar found in kidney transplant:
hockey stick scar/incision - anterior abdomen
Where is implanted kidney palpable
in the iliac fossa area
Anastamoses made between implanted kidney and patient:
Pelvic vessels - usually external iliac vessels
Ureter of donor kidney anastamosed directly with bladder
immunosuppression regime classically given post transplant: (x3)
Tacrolimus
Mycophenolate
Prednisolone
Other possible immunosuppressants:
Cyclosporine
Sirolimus
Azathioprine
Post transplant complications (relating to transplant)
- Transplant rejection (Hyperaccute, acute, chronic)
- Transplant failure
- Electrolyte imbalances
Post transplant complications (relating to immunosupression)
Ischaemic heart disease
Type 2 diabetes (steroids)
Infections are more likely and more severe
Unusual infections can occur (PCP, CMV, PJP and TB)
Non-Hodgkin lymphoma
Skin cancer (particularly squamous cell carcinoma)
