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Nephrology > Renal Review - Associations by words > Flashcards

Renal Review - Associations by words Flashcards

1
Q

If you see…

A

Think:

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2
Q

NSAIDS

A

minimal change GN in kids

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3
Q

p-ANCA

A

Churg Strauss and Microscopic polyangiitis

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4
Q

c-ANCA

A

Granulomatous polyangiitis

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5
Q

Alpha-5 chain of Type IV collagen

A

X linked Alport Syndrome

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6
Q

Alpha-3 or 4 chain of Type IV collagen:

A

autosommal recessive Anti-GBM disease (good pastures)

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7
Q

Hep B and C infection:

A

Polyarteritis Nodosa, Membranous nephropathy

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8
Q

Fibrosis of media and disruption of EM

A

Polyarteritis Nodosa

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9
Q

Hyaline glomeruli; BM and podocytes on EM

A

Membranous Nephropathy

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10
Q

Hep C infection

A

Membranoproliferative GN

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11
Q

HIV

A

FSGS

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12
Q

Von willebrand factor protease

A

TTP (thrombocytopenic purpura)

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13
Q

FAT RN (fever, anemia, thrombocytopenia, renal and neural involvement) in 30-40yo F

A

TTP

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14
Q

SPEP, UPEP

A

Amyloidosis (SPEP and UPEP are serum proteins)

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15
Q

Thrombi and fibrinoid necrosis in capillaries and arterioles

A

thrombotic microangiopathy (TMA) – TTP (thrombocytopenia purport) and hemolytic uremic syndrome (HUS) are two types

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16
Q

Shiga-like toxin:

A

classic HUS (hemolytic-uremic syndrome) – bloody diarrhea + ARF (more children) if classic; no diarrhea and insidious if atypical (adults >children)

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17
Q

Factor H defects / Genetic defects in alternative complement pathway activation:

A

atypical HUS –> TMA

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18
Q

Anti-phospholipase A2 Receptor Ab

A

Membranous Nephropathy

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19
Q

Antiphospholipid antibody syndrome

A

SLE, can cause thrombotic microangiopathy

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20
Q

Pulmonary hemorrhage

A

anti-GBM disease

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21
Q

Hemoptysis

A

Wegeners and goodpasture

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22
Q

Dominant IgA staining on IF

A

IgA nephropathy

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23
Q

Arteriolar hyalinosis

A

benign nephrosclerosis

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24
Q

Petechial hemorrhages

A

malignant HTN

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25
Onion skinning
malignant HTN, chronic transplant rejection
26
URT involvement
Wegeners/ Granulomatosis Polyangiitis (cANCA)
27
Sinus problems
Wegeners (C-Anca) and Microscopic Polyangiitis (P-ANCA)
28
Lung Involvement
Goodpasture, Churg Strauss, Wegeners
29
Digalactoside residue
ecoli fimbriae adhere to
30
Thyroidization
chronic pyelonephritis
31
Proliferation of lymphocytes and presence of neutrophils in interstitium
chronic pyelonephritis
32
Granular C3, IgG
Post-Strept GN, MPGN-I
33
Linear C3, IgG
anti-GBM
34
C3 ONLY intramembranous deposits
MPGN-II
35
Granular IgG
Membranous nephropathy
36
No deposits by IF/EM
granulomatosis polyangiitis (wegeners,cANCA ), microscopic polyangiitis (cANCA), Churg Strauss (pANCA), Crescentic GN (pANCA)
37
Presence of neutrophils in capillaries
post-strept GN or pyelonephritis
38
Sub-epithelial "humps"
post-strept GN
39
Intraluminal hyaline thrombi
SLE
40
Wire Loops
SLE
41
High ASO
post-strept GN
42
Anti proteinase 3 Ab
Wegeners
43
Pyelo caused by which bacteria?
ecoli, enterboacter, proteus, klebs pneumonia, staph saprophyticus
44
Decreased renal size, renal cortical thinning, granular cortical surface
Nephrosclerosis (can be benign)
45
Leg Edema
Nephrotic syndrome
46
Most common complication for CKD
CVD
47
Thyrotoxic periodic paralysis
hypokalemia due to decreased ion channels
48
Maltese cross
Nephrotic syndrome
49
Macroglossia or CHF
Amyloidosis
50
Fibrils in mesangium
amyloidosis
51
Hyponatremia from a diuretic
HCTZ
52
Schistosomiasis
Squamous cell carcinoma
53
Persistent urachus and extrophy
adenocarcinoma
54
Spike & dome (diffuse sub-epithelial deposits)
membranous nephropathy
55
Sup-epithelial deposits, nephritic
Post-infectious GN
56
Sub-endothelial deposits
MPGN-I or SLE
57
intramembranous deposits
MPGN-II or anti-GBM
58
Intracapillary lipds with non-specific trapping of plasma proteins
FSGS
59
Cholesterol clefts and foamy macropahges
Chronic transplant rejection
60
Glomerular BM thickening and mesangial matrix increase
diabetic nephropathy
61
Mesangial deposits
IgA nephropathy
62
Responds to empiric course of steroid tx
Minimal change glomerulonephropathy
63
Treat with plasmapheresis
anti GBM and TTP
64
Episodic hematuria + proteinurea
IgA nephropathy
65
Celiacs
IgA nephropathy
66
Sickle cell
Can't concentrate urine as much
67
Bivalent cations
thick ascending tubules
68
Asymptomatic hematuria
IgA nephropathy
69
Mesangial proliferation
IgA nephropathy
70
Diffuse mesangial expansion + nephrotic
diabetic nephropathy
71
high serum phosphate, low vitD, low Ca
increased PTH in CKD
72
Lithium
Prevents translocation of aquaporin (prevents ADH)
73
Multiple myeloma
Tubular interstitial nephritis
74
Eosinophils and history of asthma
Churg Strauss

Nephrology (2 decks)

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