Renal Review - Associations by words Flashcards

1
Q

If you see…

A

Think:

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2
Q

NSAIDS

A

minimal change GN in kids

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3
Q

p-ANCA

A

Churg Strauss and Microscopic polyangiitis

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4
Q

c-ANCA

A

Granulomatous polyangiitis

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5
Q

Alpha-5 chain of Type IV collagen

A

X linked Alport Syndrome

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6
Q

Alpha-3 or 4 chain of Type IV collagen:

A

autosommal recessive Anti-GBM disease (good pastures)

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7
Q

Hep B and C infection:

A

Polyarteritis Nodosa, Membranous nephropathy

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8
Q

Fibrosis of media and disruption of EM

A

Polyarteritis Nodosa

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9
Q

Hyaline glomeruli; BM and podocytes on EM

A

Membranous Nephropathy

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10
Q

Hep C infection

A

Membranoproliferative GN

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11
Q

HIV

A

FSGS

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12
Q

Von willebrand factor protease

A

TTP (thrombocytopenic purpura)

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13
Q

FAT RN (fever, anemia, thrombocytopenia, renal and neural involvement) in 30-40yo F

A

TTP

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14
Q

SPEP, UPEP

A

Amyloidosis (SPEP and UPEP are serum proteins)

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15
Q

Thrombi and fibrinoid necrosis in capillaries and arterioles

A

thrombotic microangiopathy (TMA) – TTP (thrombocytopenia purport) and hemolytic uremic syndrome (HUS) are two types

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16
Q

Shiga-like toxin:

A

classic HUS (hemolytic-uremic syndrome) – bloody diarrhea + ARF (more children) if classic; no diarrhea and insidious if atypical (adults >children)

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17
Q

Factor H defects / Genetic defects in alternative complement pathway activation:

A

atypical HUS –> TMA

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18
Q

Anti-phospholipase A2 Receptor Ab

A

Membranous Nephropathy

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19
Q

Antiphospholipid antibody syndrome

A

SLE, can cause thrombotic microangiopathy

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20
Q

Pulmonary hemorrhage

A

anti-GBM disease

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21
Q

Hemoptysis

A

Wegeners and goodpasture

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22
Q

Dominant IgA staining on IF

A

IgA nephropathy

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23
Q

Arteriolar hyalinosis

A

benign nephrosclerosis

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24
Q

Petechial hemorrhages

A

malignant HTN

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25
Q

Onion skinning

A

malignant HTN, chronic transplant rejection

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26
Q

URT involvement

A

Wegeners/ Granulomatosis Polyangiitis (cANCA)

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27
Q

Sinus problems

A

Wegeners (C-Anca) and Microscopic Polyangiitis (P-ANCA)

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28
Q

Lung Involvement

A

Goodpasture, Churg Strauss, Wegeners

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29
Q

Digalactoside residue

A

ecoli fimbriae adhere to

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30
Q

Thyroidization

A

chronic pyelonephritis

31
Q

Proliferation of lymphocytes and presence of neutrophils in interstitium

A

chronic pyelonephritis

32
Q

Granular C3, IgG

A

Post-Strept GN, MPGN-I

33
Q

Linear C3, IgG

A

anti-GBM

34
Q

C3 ONLY intramembranous deposits

A

MPGN-II

35
Q

Granular IgG

A

Membranous nephropathy

36
Q

No deposits by IF/EM

A

granulomatosis polyangiitis (wegeners,cANCA ), microscopic polyangiitis (cANCA), Churg Strauss (pANCA), Crescentic GN (pANCA)

37
Q

Presence of neutrophils in capillaries

A

post-strept GN or pyelonephritis

38
Q

Sub-epithelial “humps”

A

post-strept GN

39
Q

Intraluminal hyaline thrombi

A

SLE

40
Q

Wire Loops

A

SLE

41
Q

High ASO

A

post-strept GN

42
Q

Anti proteinase 3 Ab

A

Wegeners

43
Q

Pyelo caused by which bacteria?

A

ecoli, enterboacter, proteus, klebs pneumonia, staph saprophyticus

44
Q

Decreased renal size, renal cortical thinning, granular cortical surface

A

Nephrosclerosis (can be benign)

45
Q

Leg Edema

A

Nephrotic syndrome

46
Q

Most common complication for CKD

A

CVD

47
Q

Thyrotoxic periodic paralysis

A

hypokalemia due to decreased ion channels

48
Q

Maltese cross

A

Nephrotic syndrome

49
Q

Macroglossia or CHF

A

Amyloidosis

50
Q

Fibrils in mesangium

A

amyloidosis

51
Q

Hyponatremia from a diuretic

A

HCTZ

52
Q

Schistosomiasis

A

Squamous cell carcinoma

53
Q

Persistent urachus and extrophy

A

adenocarcinoma

54
Q

Spike & dome (diffuse sub-epithelial deposits)

A

membranous nephropathy

55
Q

Sup-epithelial deposits, nephritic

A

Post-infectious GN

56
Q

Sub-endothelial deposits

A

MPGN-I or SLE

57
Q

intramembranous deposits

A

MPGN-II or anti-GBM

58
Q

Intracapillary lipds with non-specific trapping of plasma proteins

A

FSGS

59
Q

Cholesterol clefts and foamy macropahges

A

Chronic transplant rejection

60
Q

Glomerular BM thickening and mesangial matrix increase

A

diabetic nephropathy

61
Q

Mesangial deposits

A

IgA nephropathy

62
Q

Responds to empiric course of steroid tx

A

Minimal change glomerulonephropathy

63
Q

Treat with plasmapheresis

A

anti GBM and TTP

64
Q

Episodic hematuria + proteinurea

A

IgA nephropathy

65
Q

Celiacs

A

IgA nephropathy

66
Q

Sickle cell

A

Can’t concentrate urine as much

67
Q

Bivalent cations

A

thick ascending tubules

68
Q

Asymptomatic hematuria

A

IgA nephropathy

69
Q

Mesangial proliferation

A

IgA nephropathy

70
Q

Diffuse mesangial expansion + nephrotic

A

diabetic nephropathy

71
Q

high serum phosphate, low vitD, low Ca

A

increased PTH in CKD

72
Q

Lithium

A

Prevents translocation of aquaporin (prevents ADH)

73
Q

Multiple myeloma

A

Tubular interstitial nephritis

74
Q

Eosinophils and history of asthma

A

Churg Strauss