Renal reabs, secretion and anatomy

Question 1

What is reabsorbed and secreted in the PCT?

Answer 1

Reabs:
Na (65%), glucose (100%), K (65%), Ca (67%)

Secretions
organic base

Question 2

What are the pri transporters of the PCT?

Answer 2

Na+/H+
Na/glucose
Aquaporin

Question 3

What is reabsorbed and secreted in the DCT?

Answer 3

reabsorption
Na (5%), Cl

Secretion
K and H

Question 4

what are the transporters of DCT?

Answer 4

Na/Cl
aldosterone sentitive Na channels

Question 5

What are the features of the DCT?

Answer 5

Principle cells

a-intercalted cells (H on apical)
b-intercalated cells (H on basolateral)

Question 6

what is the function of the DCT?

Answer 6

fine-tuning of electrolyte balance

site of action for thiazide Diuretics

Question 7

What is reabsorbed and secreted in the CD?

Answer 7

Reabs: water (ADH), Na (aldosterone), HCO3

Secretion: K+ and H+

Question 8

What are the channels for the CD?

Answer 8

aquaporin (ADH)
Na channels (aldosterone sensitive)

Question 9

What is the function of the CD?

Answer 9

final regulation urine volume and composition

site of action for ADH and Aldosterone

Question 10

what is reabsorbed and secreted in the thin descending limb?

Answer 10

Reabs
-water

Question 11

What is the function of the Thin Descending limb?

Answer 11

creates conc gradient

Question 12

What is reabs and secreted in the thick ascending?

Answer 12

reabs: Na(25%), K (20%) and Cl (20%)

Question 13

what is the role of the Thick Ascending limb?

Answer 13

Generate medullary conc

loop diuretics