Renal Quiz Flashcards

1
Q

Diuretic Categories

A
Thiazide
Loop
Carbonic anhydrase inhibitor
Potassium sparing
Osmotic
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2
Q

what do thiazides do

A

block Cl pump in ascending and distal tubules

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3
Q

urine volume is not increased in which diuretic

A

thiazide

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4
Q

adverse effects for thiazides

A

hypokalemia
altered BG
decreased Ca excretion

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5
Q

indications for thiazide

A

edema

hypertension (safe)

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6
Q

contraindications for thiazides

A

allergy

fluid/elec imbalances

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7
Q

thiazides should not be used with what drugs

A

lithium

digoxin (K falls in both)

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8
Q

should you keep drinking water on diuretics

A

yes or else rebound fluid

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9
Q

thiazide drug

A

hydrochlorothiazide (HydroDIURIL)

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10
Q

what do loops do

A

block Cl pump in ascending and descending loop of henle and DCT

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11
Q

what do you lose with loops

A

Na
Cl
Copious fluid

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12
Q

indications for loops

A

CHF
edema
too powerful for HTN

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13
Q

contraindications for loops

A

elec depletion

anuria

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14
Q

what supplements will be given with loops

A

Vitamin K

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15
Q

adverse effects of loops

A

low elec
alkalosis
reversible hearing loss

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16
Q

what will treat dig toxicity

A

water, K and salt

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17
Q

loop drug

A

furosemide (Lasix)

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18
Q

what do CAI do

A

block carbonic anhydrase

slow movement of H+

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19
Q

what do you lose with CAI

A

Na

Bicarb (urine becomes basic)

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20
Q

indications for CAI

A

angle open glaucoma

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21
Q

contraindications for CAI

A

angle closure glaucoma (can cause blindness if pressure is not released)

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22
Q

adverse effects of CAI

A
basic urine
metabolic acidosis
paresthesias
confusion
drowsiness
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23
Q

what drugs cannot be used with CAI

A

salicylates (toxic)
lithium (TF)
sulfa drugs (rxn)

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24
Q

CAI drug

A

acetazolamide (Diamox)

25
what do potassium sparing drugs do
cause Na loss retain K block aldosterone in distal tubule
26
indications for potasssium sparing
with thiazide or loop risk for hypokalemia hyperaldosteronism
27
contraindications for potassium sparing
hyperkalemia renal disease anuria
28
adverse effect of potassium sparing
hyperkalemia
29
what causes TF in potassium sparing
aspirin
30
potassium sparing drug
spironolactone (Aldactone)
31
what do osmotics do
pull water into tubule without Na loss
32
indications for osmotics
ICP or acute renal failure from MODS drug overdose trauma
33
contraindications for osmotics
``` renal disease anuria pulmonary congestion IC bleeding CHF ```
34
adverse effects of osmotics
hypovolemic shock
35
osmotic drug
mannitol
36
what to assess with diuretics
``` measure edema daily weight I&Os BUN Creatinine ```
37
signs of acute pyelonephritis
chills flank pain fever tenderness
38
what do anti-infectives do
destroy bacteria in urinary tract
39
what should you always ask before anti-infectives
allergies! (reactions are very strong)
40
keys to healing from UTI
perineal hygiene | increased fluid intake
41
anti-infective drugs
ciprofloxacin (Cipro) | nitrofurantoin (Furadantin)
42
what do antispasmodics do
block spasms of urinary tract block PNS activity = anticholinergic relax detrusor an other muscles
43
indications for antispasmodics
bladder spasm | dysuria
44
contraindications for antispasmodics
glaucoma myasthenia gravis GI obstructions acute hemorrhage
45
antispasmodic drug
oxybutynin (Ditropan)
46
what do UT analgesias do
exerts topical analgesic effect on urinary mucosa
47
indications for UT analgesics
relief of symptoms from UTI
48
adverse effect of UT analgesics
red-orange urine
49
UT anagesia drug
phenazopyridine (Azo Standard)
50
what do bladder protectants do
adheres to bladder wall and acts as a buffer to control cell permeability prevents irritating solutes in urine from reaching bladder
51
indications for bladder protectants
interstitial cystitis
52
contraindications of bladder protectants
bleeding conditions
53
badder protectant drug
pentosan polysulfate (Elmiron)
54
what do alpha adrenergic blockers do
block receptors in SNS
55
adverse effects of alpha adrenergic blockers
tachycardia hypotension sexual dysfunction
56
alpha adrenergic blocker drugs
doxazosin (Cardura) | tamsulosin (Flomax)
57
what do testosterone blockers do
inhibit intracellular enzyme that converts test to DHT which develops and maintains the prostate gland
58
adverse effects of testosterone blockers
decreased libido impotence no blood donations for 6 months
59
testosterone blocker drug
finasteride (Propecia)