GI Quiz Flashcards
Categories for GERD/ULCER disease
Histamine 2 antagonists Antacids PPI GI protectant Prostaglandins
Where are the H2 receptors
stomach parietal cells
What do the H2 do
make acid
-dine
H2 antagonists
Drug that is cardio protective in CHF
H2 antagonists
Indications for H2 antagonists
Short term treatment of active duodenal ulcer, benign gastric ulcer and GERD
If you use H2 antagonists/PPI long term
increased risk for cell malfunction = stomach cancer
need problem fixed
H2 antagonist drug
ranitidine (Zantac)
What do antacids do
neutralize stomach acid by direct chemical reaction
Bicarb corrects
acidosis
Indications for antacids
symptomatic relief of upset stomach from hyperacidity and hyperactivity
Antacids contraindicated with
GI obstruction
Conditions exacerbated by electrolyte imbalance
Adverse effects of antacids
rebound acidity
alkalosis
Drug that should be taken separate from other food/drugs
antacids
Systematically alkalotic
headache
nausea
vomiting
muscle twitching
Antacid drug
aluminum salts (AlternaGEL)
What do PPIs do
prevent final step of acid production
Indications for PPI
short term treatment
treat H pylori
Adverse reactions of PPI
C diff, increased bone loss
PPI drug
omeprazole (Prilosec)
what do GI protectants do
form ulcer-adherent complex at duodenal ulcer sites
Indications for GI protectants
promote ulcer healing
Adverse effects of GI protectants
GI effects (including dry mouth)
Drug won’t get bound if given with food
GI protectant