GI Quiz Flashcards

1
Q

Categories for GERD/ULCER disease

A
Histamine 2 antagonists
Antacids
PPI
GI protectant
Prostaglandins
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2
Q

Where are the H2 receptors

A

stomach parietal cells

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3
Q

What do the H2 do

A

make acid

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4
Q

-dine

A

H2 antagonists

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5
Q

Drug that is cardio protective in CHF

A

H2 antagonists

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6
Q

Indications for H2 antagonists

A

Short term treatment of active duodenal ulcer, benign gastric ulcer and GERD

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7
Q

If you use H2 antagonists/PPI long term

A

increased risk for cell malfunction = stomach cancer

need problem fixed

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8
Q

H2 antagonist drug

A

ranitidine (Zantac)

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9
Q

What do antacids do

A

neutralize stomach acid by direct chemical reaction

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10
Q

Bicarb corrects

A

acidosis

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11
Q

Indications for antacids

A

symptomatic relief of upset stomach from hyperacidity and hyperactivity

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12
Q

Antacids contraindicated with

A

GI obstruction

Conditions exacerbated by electrolyte imbalance

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13
Q

Adverse effects of antacids

A

rebound acidity

alkalosis

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14
Q

Drug that should be taken separate from other food/drugs

A

antacids

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15
Q

Systematically alkalotic

A

headache
nausea
vomiting
muscle twitching

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16
Q

Antacid drug

A

aluminum salts (AlternaGEL)

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17
Q

What do PPIs do

A

prevent final step of acid production

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18
Q

Indications for PPI

A

short term treatment

treat H pylori

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19
Q

Adverse reactions of PPI

A

C diff, increased bone loss

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20
Q

PPI drug

A

omeprazole (Prilosec)

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21
Q

what do GI protectants do

A

form ulcer-adherent complex at duodenal ulcer sites

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22
Q

Indications for GI protectants

A

promote ulcer healing

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23
Q

Adverse effects of GI protectants

A

GI effects (including dry mouth)

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24
Q

Drug won’t get bound if given with food

A

GI protectant

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25
GI protectant drug
sucralfate (Carafate)
26
what do prostaglandins do
inhibit gastric acid secretion and increases bicarb/mucus production in stomach
27
indications for prostaglandins
prevent NSAID ulcers | Treat duodenal ulcers
28
Adverse effects of prostaglandins
GU effects
29
Drug that is an abortafacient
prostaglandins
30
prostaglandin drug
misoprostol (Cytotec)
31
what do pancreatic enzymes do
replace enzymes that help digestion and absorption of fats, proteins and carbohydrates
32
Indications for pancreatic enzymes
cystic fibrosis, pancreas disease and common bile duct problems
33
adverse effects of pancreatic enzymes
GI irritation, nausea, abdominal cramps and diarrhea
34
when should you take pancreatic enzymes
with meal
35
pancreatic enzyme drug
pancrelipase (Pancrease)
36
GI motility categories
laxatives GI stimulants antidiarrheals
37
who uses laxatives
elderly and women trying to lose weight
38
indications for laxatives
short term relief of constipation removal of ingested poisons evacuate bowel for procedure
39
adverse effects of laxatives
uterine contractions | cathartic dependency
40
chemical stimulant drug
bisacodyl (Dulcolax)
41
chemical stimulants do
irritate the GI tract lining
42
bulk stimulant drug
magnesium citrate (Citrate of Magnesia)
43
bulk stimulants do
cause fecal matter to increase in bulk
44
lubricant drug
docusate (Colace)
45
lubricants do
help intestinal contents move more smoothly through lubrication
46
what do GI stimulants do
block dopamine and increase Ach to stimulate PNS in GI tract | -keeps dopamine around
47
worst side effects of GI stimulants
EPS
48
GI stimulant drug
metoclopramide (Reglan)
49
what do antidiarrheals do
slow the motility of the GI tract through direct action of the lining -more water and electrolytes absorbed
50
indications for antidiarrheals
diarrhea reduction of volume from ileostomies traveler's diarrhea
51
worst adverse effect of antidiarrheals
toxic megacolon
52
how is toxic megacolon found
fever abdominal pain decreased bowel sounds
53
contraindications for antidiarrheals
poisoning | obstruction
54
antidiarrheal drug
loperamide (Imodium)
55
antiemetic categories
phenothiazines anticholinergics serotonin 5HT3 receptor blockers
56
what do phenothiazines do
depress CTZ of CNS | highly anticholinergic
57
indications for phenothiazines
n/v hiccoughs don't have many options
58
adverse effects of phenothiazines
red/brown urine sun sensitivity risk for falls
59
phenothiazine drug
promethazine (Phenergan)
60
what do anticholinergics do
act as antihistamine and block impulses to CTZ
61
indications for anticholinergics
n/v | dizziness
62
anticholinergic drug
meclizine (Antivert)
63
what do serotonin 5HT3 receptor blockers do
block n/v receptors in CTZ
64
indications for serotonin 5HT3 receptor blockers
control n/v associated with chemo
65
adverse effects of serotonin 5HT3 receptor blockers
myalgia urinary retention very safe
66
serotonin 5HT3 receptor blocker drug
ondansetron (Zofran)