Renal Physiology Lectures Flashcards
1
Q
What is renal clearance?
A
the volume of plasma from which a substance is completely removed/unit time
Clearance = Ux x V / Px
Ux - concentration in the urine
V - rate of urine production
Px - concentration in the plasma
2
Q
What is the volume of plasma?
A
3000mL
use this to turn an amount of drug in the plasma into a CONCENTRATION
3
Q
What is the Henderson-Hasselbach equation for acidic drugs?
A
pH = pKa + log (A-/AH)
