renal physiology Flashcards
1
Q
what are the key function of the kidney?
A
homeostasis: • filtration and reabsorption of water and electrolytes • BP control • K+ Vitamin D activation EPO
2
Q
Which substances undergo net excretion in the kidney into the urine?
A
sodium
phosphate
potassium
uraemic toxins
3
Q
what is GFR?
A
the volume of blood filtered by the kidneys per min
4
Q
How much of the cardiac output do both kidneys take?
A
20%
5
Q
How do we stage the severity of CKD?
A
by eGFR value
6
Q
what are some complications of CKD?
A
anaemia
bone disease
symptoms from build up of uraemic toxins
7
Q
Why do we use eGFR and not GFR itself?
A
clinically, it is not practical to measure GFR directly, as you need a substance that is freely filtered and that your body doesn’t reabsorb or secrete afterwards and the body does not contain a substance like this
so GFR is estimated using serum creatinine
