Renal Pathology Flashcards
Minimal change disease can be diagnosed by:
a. Electron microscopy
b. Immunofluorescence
c. H and E
d. PAS
a. Electron microscopy
Possible causes of chronic pyelonephritis (2 right answers):
a. Hypertension
b. Renal artery stenosis
c. Vesico-ureteral reflux
d. Kindey stones
c. Vesico-ureteral reflux
d. Kindey stones
Systemic secondary amyloidosis leads to renal insufficiency
a. True
b. False
a. True
Main risk factor for urothelial carcinoma
a. Bacterial infection
b. Sexually transmitted diseases
c. HPV infection
d. Smoking
d. Smoking
Components of Nephrotic syndrome are, EXCEPT:
a. Proteinuria
b. Hypertension
c. Hypoalbuminemia
d. Hyperlipidemia
e. Edema
b. Hypertension
True for rapidly progressive (crescentic) glomerulonephritis, EXCEPT:
a. Progresses rapidly
b. Associated exclusively with Nephrotic syndrome
c. May occur as a manifestation of systemic disorders
d. May be preceded by post-infectious glomerulonephritis
e. Anti-GBM antibodies may be demonstrated in some cases
b. Associated exclusively with Nephrotic syndrome
What color is clear cell kidney carcinoma macroscopically?
a. White
b. Light pink
c. Yellow
d. Brown
c. Yellow
Possible causes of secondary membranous glomerulonephritis (2 correct):
a. Hepatorenal syndrome
b. Malignancy
c. SLE
d. Shock
b. Malignancy
c. SLE
Characteristic microscopic alterations in Kimmelstiel-Wilson syndrome (2 correct):
a. Nodular glomerulosclerosis
b. Arteriolosclerosis
c. Granular IgG positivity
d. Mesangial proliferation
a. Nodular glomerulosclerosis
d. Mesangial proliferation
Histological characteristic of end-stage-kidney, EXCEPT:
a. Glomerulus hypertrophy
b. Interstitial fibrosis
c. Glomerulosclerosis
d. Thyroidisation
a. Glomerulus hypertrophy
Linear deposition of IgG and/or C3 along the glomerular basement membrane is seen in (multiple answers):
a. Membranous GN
b. Anti-GBM nephritis
c. Minimal change nephropathy
d. Goodpasture syndrome
b. Anti-GBM nephritis
d. Goodpasture syndrome
Causes Nephritis syndrome, EXCEPT:
a. IgA-nephropathy
b. Minimal change disease
c. Membranoproliferative glomerulonephritis
d. Crescentic glomerulonephritis
b. Minimal change disease
Benign hypertension can lead to renal failure
a. True
b. False
b. False
The autosomal dominant polycystic kidney disease usually manifests in the neonatal period and rapidly leads to acute renal failure
a. True
b. False
b. False
90% of malignant tumors encountered in the urinary bladder are:
a. Large cell carcinoma
b. Transitional cell papilloma
c. Squamous cell carcinoma
d. Adenocarcinoma
e. Transitional cell carcinoma
e. Transitional cell carcinoma (aka Urethelial carcinoma)
Schistosomiasis may be associated with the formation of:
a. Renal cell carcinoma
b. Squamous cell carcinoma of the urinary bladder
c. Adenocarcinoma of the urinary bladder
d. Wilms tumor
e. Neuroblastoma
b. Squamous cell carcinoma of the urinary bladder
True for lipoid nephrosis (2 correct)
a. Virtually normal glomeruli on routine microscopic examination
b. Minimal response to corticosteroid therapy
c. The most frequent cause of nephrotic syndrome in children
d. Most commonly affects adults
a. Virtually normal glomeruli on routine microscopic examination
c. The most frequent cause of nephrotic syndrome in children
True for clear cell carcinoma of the kidney (2 right answers):
a. Frequent degeneration in the tumor parenchyma
b. It is a desmoplastic tumor
c. It is the most frequent local kidney lesion
d. Generally diagnosed incidentally
a. Frequent degeneration in the tumor parenchyma
c. It is the most frequent local kidney lesion
Possible complications of the kidney in diabetes patient (2 answers)
a. Glomerulosclerosis
b. Papilla necrosis
c. Glumerulonephritis
d. Acute tubular necrosis
a. Glomerulosclerosis
b. Papilla necrosis
Urothelial carcinoma has high risk of local recurrence
a. True
b. Flase
a. True
Most common tumor type in the urinary bladder:
a. Leiomyosarcoma
b. Adenocarcinoma
c. Urotelial carcinoma
d. Squamous cell carcinoma
c. Urotelial carcinoma
Mostly affected gene in clear cell renal cell carcinoma:
a. BRCA
b. VHL
c. WT-1
d. p53
b. VHL
Typical histological feature of acute suppurative pylonephritis:
a. Interstitial fibrosis
b. Crescent formation in the glomerulus.
c. Infiltration of neutrophils and abscesses in the interstitium and in tubules
d. Flattened epithelium in the pyelon
c. Infiltration of neutrophils and abscesses in the interstitium and in tubules
Typical histological feature of acute suppurative pylonephritis:
a. Interstitial fibrosis
b. Crescent formation in the glomerulus.
c. Infiltration of neutrophils and abscesses in the interstitium and in tubules
d. Flattened epithelium in the pyelon
c. Infiltration of neutrophils and abscesses in the interstitium and in tubules
