Renal Patho Flashcards

1
Q

Glomeruloneuropathies

A
  • Decreased glomerular filtration
    • Decreased urine output
    • Increase plasma creatinine and urea
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2
Q

Nephrosis

A
  • Damage to glomerular membrane
  • Enlargement of fenestrations
  • Excretion of or more 3.5 g of protein in urine /day
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3
Q

Clinical manifestations of nephrosis

A

Edema

Hypotension

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4
Q

Nephrosis causes

A
  • Hypertension
  • Dibetes mellitus, destruction of capillary beds in glomerulus
  • Type 3 immune complex, immune disorders
    • Lupus
    • Rheumatoid arthritis
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5
Q

3 types of nephrosis

A
  • Minimal change diseases
  • Fecal segmental
  • Membranous
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6
Q

Minimal change disease

A
  • Most common form in children
  • Loss of foot processes
  • Good prognosis
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7
Q

Fecal segmental glomerulosclerosis

A
  • Scarring of glomerulus
  • primary or secondary
  • Poor prognosis
  • 3 Hs
    • HIV, heroin, hypertension
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8
Q

Membranous Glomerulonephritis

A
  • Autoimmune activation of immune complex
  • Deposition of antibodies in basement mebrane
  • Increased mebrane permeability and thickening
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