Renal Neoplasms Flashcards
Oncocytoma, think…
Benign Mitochondria rich eosinophilic cytoplasm Granular appearance Central Stellate scar Mohogany brown coloration
Angiomyolipoma, think…
Benign mesenchymal
Blood vessels involved, fat on gross pathology
Presenting clinical picture of renal neoplasms…
Dull flank pain
Hematuria
Clear cell, think…
Malignant Polar, yellow color Chromosome 3 mutation (sporadic) VHL mutation (hereditary) venous invasion
Papillary carcinoma, think…
Malignant Bilateral and multifocal Acquired dialysis Fingerlike projections Trisomy 7 or activated MET
Chromophobe carcinoma, think…
Large pale cells
Positive for hales colloidal iron stain
Renal pelvis carcinoma, think…
Papillary adenocarcinoma (transitional cell carcinoma) due to smoking
Epidermoid (squamous cell) carcinoma due to inflammation
Smoking related disease!
Wilms tumor/nephroblastoma, think…
Most common pediatric tumor of kidney
Mixture of cellular elements
Palpable mass on presentation
Metastatic cancer, think…
Multifocal
Bilateral
(most neoplasms of kidney are focal and unilateral)
All renal cancers are radio-______
Resistant
All renal cancers are radio-______
Resistant
