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Renal > Renal Neoplasms > Flashcards

Renal Neoplasms Flashcards

1
Q

MC Primary Renal Cancer

A

Renal Cell Carcinomas from renal cortex

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2
Q

MC Bladder Cancer

A

Urothelial (Transitional Cell Carcinomas) from renal pelvis

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3
Q

MC Renal Cell Carcinoma Subtype

A

Clear Cell from proximal tubule

  1. Clear Cell
  2. Papillary
  3. Chromophobe
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4
Q

Which Renal Cell Carcinoma has the worst prognosis?

A

Clear Cell

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5
Q

Having the Von Hippel-Lindau gene puts you at higest risk for which type of Renal Neoplasm?

A

Clear Cell (subtype of Renal Cell Carcinoma)

worst prognosis subtype

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6
Q

Socioeconomic factors that put you at highest risk for Renal Cell Carcinoma?

A

64yo BLACK MALE

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7
Q

Risk factors of Renal Cell Carcinoma

A
  1. Smoking
  2. HTN (doesnt matter if controlled or not)
  3. Obesity
  4. Chemicals (Cadmium, Asbestos, Petroleum byproducts)
  5. Acquired Polycystic Kidney Dz
  6. Hx Chronic Hep C
  7. SICKLE CELL TRAIT
  8. DM (iffy)
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8
Q

Renal Cell Carcinoma “Classic Triad”

A

Flank pain
Hematuria
Palpable Abd Mass

Also -> Wt loss (not part of triad)
Most patients with renal cell carcinoma will be asymptomatic and present with advanced dz

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9
Q

MC CBC finding for RCC

A

Anemia

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10
Q

Order a ____ for Definitive Dx of RCC

A

Bx

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11
Q

A 74 year old presents with Flank pain/Hematuria/Palpable abdominal renal mass. Wife states he has been more confused. Which is the best study to order for this patient?

A

Brain MRI

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12
Q

RCC + Neuro SS -> Order a ____

A

Brain MRI

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13
Q

RCC + Bone Pain or HIGH Alk Phosph -> Order a _____

A

Bone Scan

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14
Q

RCC

Order a ___ to r/o metastases

A

CXR or CT Chest

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15
Q

RCC

Order a _____ to see what the mass is made up of and to stage it

A

CT or MRI

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16
Q

Renal Cell Carcinomas > _____cm require Sx Radial Nephrectomy

A

7

Radial Nephrectomy = removes the whole kidney, the fatty tissues surrounding the kidney and a portion of the tube connecting the kidney to the bladder (ureter)

17
Q

Trmnt for Metastatic RCC

A

Chemo
* Monoclonal antibodies (Pembrolizumab PD-1 inhibitor)
* Tyrosine Kinase Inhibitor/ Vascular Endothelial Growth Factor (VEGF) Inhibitor (Sunitinib-inhibits tumor cell growth)

18
Q

RCC Complications

A
  • Paraneoplastic Syndrome
  • Stauffer’s Syndrome

Renal (6 decks)

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