Congenital Flashcards

1
Q

MC inherited form of kidney disease

A

ADPKD
Autosomal Dominant Polycystic Kidney Disease

PKD1 & PKD2 gene variations
PDK1 is worse

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2
Q

MC renal stone in ADPKD?

A

Uric Acid

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3
Q

Imaging Order for pt with (+) FMH of ADPKD

A

Renal US

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4
Q

Autosomal Dominant Polycystic Kidney Disease

HTN trmnt:
BP Goal?
Rx?

A

BP Goal: 100/75
ACE-I or ARB

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5
Q

Pyelonephritis Trmnt for those with ADPCKD

A

ABX (4-6wks)
* Bactrim
* Quinolones
* Chloramphenicol

Lipid soluble ABX penetrate cyst walls the best

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6
Q

Trmnt for ADPKD pt at high risk for ESRD

A

Tolvaptan

(Vasopressin V2-receptor antagonist)
MOA: Incr free water excretion -> decr risk of renal stones & slows cyst progression

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7
Q

In those with ADPKD, order a _____ to differentiate b/w Cystic Dz vs Cancer

A

CT or MRI

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