Congenital Flashcards
1
Q
MC inherited form of kidney disease
A
ADPKD
Autosomal Dominant Polycystic Kidney Disease
PKD1 & PKD2 gene variations
PDK1 is worse
2
Q
MC renal stone in ADPKD?
A
Uric Acid
3
Q
Imaging Order for pt with (+) FMH of ADPKD
A
Renal US
4
Q
Autosomal Dominant Polycystic Kidney Disease
HTN trmnt:
BP Goal?
Rx?
A
BP Goal: 100/75
ACE-I or ARB
5
Q
Pyelonephritis Trmnt for those with ADPCKD
A
ABX (4-6wks)
* Bactrim
* Quinolones
* Chloramphenicol
Lipid soluble ABX penetrate cyst walls the best
6
Q
Trmnt for ADPKD pt at high risk for ESRD
A
Tolvaptan
(Vasopressin V2-receptor antagonist)
MOA: Incr free water excretion -> decr risk of renal stones & slows cyst progression
7
Q
In those with ADPKD, order a _____ to differentiate b/w Cystic Dz vs Cancer
A
CT or MRI