Renal Neoplasia Flashcards
Angiomyolipoma
association
tuberosclerosis
Hematuria
Palpable mass
Flank pain
what is it?
renal cell carcinoma
Renal cell carcimona
classic triad
+ common presentation sidebar
hematuria
palpable mass
flank pain
+ paraneplastic syndrome
(HTN, polycythemia)
Anatomic abnormality
in renal cell carcioma
possibility
left-sided varicocele
*tumors like to metastisize to renal vein
*remember on left side that left testicular vein drains into left renal vein
*not the same on the right side
Most common renal cell carconima subtype
clear-cell
*clear cytoplasm on H&E
Most common mutation leading to renal cell carcinoma
VHL (3p)
tumor suppressor gene
Major risk factor for renal cell carcinoma
cigarette smoking
Disease causing hereditary renal cell carcinoma
Von Hippel-Lindau disease
Von Hippel-Lidau Disease
causes what?
hereditary VHL mutation
renal cell carcinoma
hemangioblastoma of the cerebellum
Wilms Tumor
presentation
3 y/o child
large, unilateral flank mass
hematuria
HTN
WAGR syndrome
Wilms tumor
Aniridia
Genital abnormalities
mentan and motor Retardation
